John E Pimanda
Overview
Explore the profile of John E Pimanda including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
90
Citations
3631
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Lee Q, Padula M, Pinello N, Williams S, ORourke M, Fumagalli M, et al.
PLoS Pathog
. 2020 Jan;
16(1):e1008262.
PMID: 31971979
Mouse kidney parvovirus (MKPV) is a member of the provisional genus Chapparvovirus that causes renal disease in immune-compromised mice, with a disease course reminiscent of polyomavirus-associated nephropathy in immune-suppressed kidney...
22.
Krivtsov A, Evans K, Gadrey J, Eschle B, Hatton C, Uckelmann H, et al.
Cancer Cell
. 2019 Dec;
36(6):660-673.e11.
PMID: 31821784
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-based design yielded the potent, highly selective, and orally bioavailable small-molecule...
23.
Richards L, Kumari A, Knezevic K, Thoms J, von Jonquieres G, Napier C, et al.
Haematologica
. 2019 Aug;
105(6):1517-1526.
PMID: 31413099
Telomerase is a ribonucleoprotein complex that maintains the length and integrity of telomeres, and thereby enables cellular proliferation. Understanding the regulation of telomerase in hematopoietic cells is relevant to the...
24.
Thoms J, Beck D, Pimanda J
Genes Chromosomes Cancer
. 2019 Aug;
58(12):859-874.
PMID: 31369171
Acute myeloid leukemia (AML) is a complex disease characterized by a diverse range of recurrent molecular aberrations that occur in many different combinations. Components of transcriptional networks are a common...
25.
Poulos R, Perera D, Packham D, Shah A, Janitz C, Pimanda J, et al.
JNCI Cancer Spectr
. 2019 Jul;
3(2):pkz012.
PMID: 31360895
Background: Genetic testing of cancer samples primarily focuses on protein-coding regions, despite most mutations arising in noncoding DNA. Noncoding mutations can be pathogenic if they disrupt gene regulation, but the...
26.
Chiu S, Orive S, Moon M, Saw J, Ellis S, Kile B, et al.
Blood
. 2019 Jul;
134(10):826-835.
PMID: 31300405
The stem cell leukemia (Scl or Tal1) protein forms part of a multimeric transcription factor complex required for normal megakaryopoiesis. However, unlike other members of this complex such as Gata1,...
27.
Kumar P, Beck D, Galeev R, Thoms J, Safaee Talkhoncheh M, de Jong I, et al.
Blood Adv
. 2019 Feb;
3(4):681-691.
PMID: 30808686
Identification of determinants of fate choices in hematopoietic stem cells (HSCs) is essential to improve the clinical use of HSCs and to enhance our understanding of the biology of normal...
28.
Jing D, Huang Y, Liu X, Sia K, Zhang J, Tai X, et al.
Cancer Cell
. 2018 Dec;
34(6):906-921.e8.
PMID: 30537513
Glucocorticoids play a critical role in the treatment of lymphoid malignancies. While glucocorticoid efficacy can be largely attributed to lymphocyte-specific apoptosis, its molecular basis remains elusive. Here, we studied genome-wide...
29.
Jacquelin S, Straube J, Cooper L, Vu T, Song A, Bywater M, et al.
Blood
. 2018 Oct;
132(26):2707-2721.
PMID: 30366920
Myeloproliferative neoplasms (MPNs) are a group of blood cancers that arise following the sequential acquisition of genetic lesions in hematopoietic stem and progenitor cells (HSPCs). We identify mutational cooperation between...
30.
Chiu S, Saw J, Huang Y, Sonderegger S, Wong N, Powell D, et al.
Development
. 2018 Sep;
145(19).
PMID: 30185409
Stem cell leukemia ( or ) and lymphoblastic leukemia 1 () encode highly related members of the basic helix-loop-helix family of transcription factors that are co-expressed in the erythroid lineage....