Ashwin Unnikrishnan
Overview
Explore the profile of Ashwin Unnikrishnan including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1015
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0
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Recent Articles
1.
Schnegg-Kaufmann A, Thoms J, Sarower Bhuyan G, Hampton H, Vaughan L, Rutherford K, et al.
Blood
. 2022 Dec;
141(11):1316-1321.
PMID: 36493342
Myelodysplastic neoplasms (MDSs) and chronic myelomonocytic leukemia (CMML) are clonal disorders driven by progressively acquired somatic mutations in hematopoietic stem cells (HSCs). Hypomethylating agents (HMAs) can modify the clinical course...
2.
Saini S, Holmberg-Thyden S, Bjerregaard A, Unnikrishnan A, Dorfmuller S, Platzbecker U, et al.
Leukemia
. 2022 Oct;
36(11):2734-2738.
PMID: 36209321
No abstract available.
3.
Amaldoss M, Yang J, Koshy P, Unnikrishnan A, Sorrell C
Drug Discov Today
. 2022 Oct;
27(12):103386.
PMID: 36182068
Inorganic nanoparticles for drug delivery in cancer treatment offer many potential advantages because they can maximize therapeutic effect through targeting ligands while minimizing off-target side-effects through drug adsorption and infiltration....
4.
Amaldoss M, Pandzic E, Koshy P, Kumar N, Sorrell C, Unnikrishnan A
Methods
. 2022 Aug;
207:11-19.
PMID: 36028162
No abstract available.
5.
Mesoderm-derived PDGFRA cells regulate the emergence of hematopoietic stem cells in the dorsal aorta
Chandrakanthan V, Rorimpandey P, Zanini F, Chacon D, Olivier J, Joshi S, et al.
Nat Cell Biol
. 2022 Jul;
24(8):1211-1225.
PMID: 35902769
Mouse haematopoietic stem cells (HSCs) first emerge at embryonic day 10.5 (E10.5), on the ventral surface of the dorsal aorta, by endothelial-to-haematopoietic transition. We investigated whether mesenchymal stem cells, which...
6.
Liu L, Vujovic A, Deshpande N, Sathe S, Anande G, Chen H, et al.
Nat Commun
. 2022 Jul;
13(1):3833.
PMID: 35781533
Chemo-resistance in acute myeloid leukemia (AML) patients is driven by leukemic stem cells (LSCs) resulting in high rates of relapse and low overall survival. Here, we demonstrate that upregulation of...
7.
Amaldoss M, Mehmood R, Yang J, Koshy P, Kumar N, Unnikrishnan A, et al.
Biomater Sci
. 2022 Jun;
10(14):3671-3694.
PMID: 35686620
Cerium-based nanoparticles (CeNPs), particularly cerium oxide (CeO), have been studied extensively for their antioxidant and prooxidant properties. However, their complete redox and enzyme-mimetic mechanisms of therapeutic action at the molecular...
8.
Liu Y, Kwon J, Fabiani E, Xiao Z, Liu Y, Follo M, et al.
N Engl J Med
. 2022 May;
386(21):1998-2010.
PMID: 35613022
Background: Although hypomethylating agents are currently used to treat patients with cancer, whether they can also reactivate and up-regulate oncogenes is not well elucidated. Methods: We examined the effect of...
9.
Yang J, Gao C, Liu M, Liu Y, Kwon J, Qi J, et al.
Cancer Res
. 2021 Oct;
81(23):6018-6028.
PMID: 34593523
Oncofetal protein SALL4 is critical for cancer cell survival. Targeting SALL4, however, is only applicable in a fraction of cancer patients who are positive for this gene. To overcome this...
10.
Lorenzi L, Chiu H, Avila Cobos F, Gross S, Volders P, Cannoodt R, et al.
Nat Biotechnol
. 2021 Jun;
39(11):1467.
PMID: 34183863
No abstract available.