John D Leszyk
Overview
Explore the profile of John D Leszyk including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
984
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites
Cherepanova N, Venev S, Leszyk J, Shaffer S, Gilmore R
J Cell Biol
. 2019 Jul;
218(8):2782-2796.
PMID: 31296534
Human cells express two oligosaccharyltransferase complexes (STT3A and STT3B) with partially overlapping functions. The STT3A complex interacts directly with the protein translocation channel to mediate cotranslational glycosylation, while the STT3B...
2.
Becerra-Artiles A, Cruz J, Leszyk J, Sidney J, Sette A, Shaffer S, et al.
Eur J Immunol
. 2019 Apr;
49(8):1167-1185.
PMID: 31020640
Human herpes virus 6B (HHV-6B) is a widespread virus that infects most people early in infancy and establishes a chronic life-long infection with periodic reactivation. CD4 T cells have been...
3.
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al.
Hum Mol Genet
. 2019 Feb;
28(13):2143-2160.
PMID: 30806671
Aberrant translational repression is a feature of multiple neurodegenerative diseases. The association between disease-linked proteins and stress granules further implicates impaired stress responses in neurodegeneration. However, our knowledge of the...
4.
Nanaware P, Jurewicz M, Leszyk J, Shaffer S, Stern L
Mol Cell Proteomics
. 2018 Dec;
18(3):490-503.
PMID: 30573663
Presentation of antigenic peptides on MHC-II molecules is essential for tolerance to self and for initiation of immune responses against foreign antigens. DO (HLA-DO in humans, H2-O in mice) is...
5.
Singh G, Kucukural A, Cenik C, Leszyk J, Shaffer S, Weng Z, et al.
Cell
. 2018 Oct;
151(4):915-916.
PMID: 30360293
No abstract available.
6.
Rittershaus E, Baek S, Krieger I, Nelson S, Cheng Y, Nambi S, et al.
Cell Chem Biol
. 2018 Oct;
25(12):1495-1505.e3.
PMID: 30318462
Upon inhibition of respiration, which occurs in hypoxic or nitric oxide-containing host microenvironments, Mycobacterium tuberculosis (Mtb) adopts a non-replicating "quiescent" state and becomes relatively unresponsive to antibiotic treatment. We used...
7.
Shin A, Shin B, Shin J, Kim K, Atwal R, Hope J, et al.
Hum Mol Genet
. 2017 Feb;
26(7):1258-1267.
PMID: 28165127
Huntington's disease (HD) reflects dominant consequences of a CAG repeat expansion mutation in HTT. Expanded CAG repeat size is the primary determinant of age at onset and age at death...
8.
Friesen W, Trotta C, Tomizawa Y, Zhuo J, Johnson B, Sierra J, et al.
RNA
. 2017 Jan;
23(4):567-577.
PMID: 28096517
Nonsense mutations resulting in a premature stop codon in an open reading frame occur in critical tumor suppressor genes in a large number of the most common forms of cancers...
9.
Cheng B, Zhou Q, Weng L, Leszyk J, Greenberg M, Tse-Dinh Y
FEBS Lett
. 2016 Dec;
591(1):28-38.
PMID: 27926785
Topoisomerases catalyze changes in DNA topology by directing the movement of DNA strands through consecutive cleavage-rejoining reactions of the DNA backbone. We describe the use of a phenylselenyl-modified thymidine incorporated...
10.
Roy B, Friesen W, Tomizawa Y, Leszyk J, Zhuo J, Johnson B, et al.
Proc Natl Acad Sci U S A
. 2016 Oct;
113(44):12508-12513.
PMID: 27702906
A premature termination codon (PTC) in the ORF of an mRNA generally leads to production of a truncated polypeptide, accelerated degradation of the mRNA, and depression of overall mRNA expression....