John Condeelis
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Explore the profile of John Condeelis including associated specialties, affiliations and a list of published articles.
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113
Citations
11945
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Recent Articles
1.
Petersen J, Du W, Adkisson C, Gravekamp C, Oktay M, Condeelis J, et al.
J Vis Exp
. 2023 Oct;
(200).
PMID: 37870314
The physiology and pathophysiology of the pancreas are complex. Diseases of the pancreas, such as pancreatitis and pancreatic adenocarcinoma (PDAC) have high morbidity and mortality. Intravital imaging (IVI) is a...
2.
Genna A, Duran C, Entenberg D, Condeelis J, Cox D
bioRxiv
. 2023 Feb;
PMID: 36824832
Macrophages are important players involved in the progression of breast cancer, including in seeding the metastatic niche. However, the mechanism by which macrophages in the lung parenchyma interact with tumor...
3.
Linder S, Cervero P, Eddy R, Condeelis J
Nat Rev Mol Cell Biol
. 2022 Sep;
24(2):86-106.
PMID: 36104625
Cell invasion into the surrounding extracellular matrix or across tissue boundaries and endothelial barriers occurs in both physiological and pathological scenarios such as immune surveillance or cancer metastasis. Podosomes and...
4.
Chellakkan Selvanesan B, Chandra D, Quispe-Tintaya W, Jahangir A, Patel A, Meena K, et al.
Sci Transl Med
. 2022 Mar;
14(637):eabc1600.
PMID: 35320003
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment. Here, we present a microbial-based immunotherapeutic treatment...
5.
Breast Cancer Cell Re-Dissemination from Lung Metastases-A Mechanism for Enhancing Metastatic Burden
Borriello L, Condeelis J, Entenberg D, Oktay M
J Clin Med
. 2021 Jun;
10(11).
PMID: 34071839
Although metastatic disease is the primary cause of mortality in cancer patients, the mechanisms leading to overwhelming metastatic burden are still incompletely understood. Metastases are the endpoint of a series...
6.
Ginter P, Karagiannis G, Entenberg D, Lin Y, Condeelis J, Jones J, et al.
Cancers (Basel)
. 2019 Oct;
11(10).
PMID: 31597373
Cancer cells metastasize from primary tumors to regional lymph nodes and distant sites via the lymphatic and blood vascular systems, respectively. Our prior work has demonstrated that in primary breast...
7.
Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al.
Oncogene
. 2019 Oct;
39(8):1830.
PMID: 31576012
The original version of this Article contained an error in the author affiliations. Vladislav V. Verkhusha was incorrectly associated with the School of Mathematics, Statistics & Applied Mathematics, National University...
8.
Marcus J, Bejerano-Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al.
Oncogene
. 2019 Jul;
38(30):5839-5859.
PMID: 31285548
The cytoskeletal interacting protein Septin 9 (SEPT9), a member of the septin gene family, has been proposed to have oncogenic functions. It is a known hot spot of retroviral tagging...
9.
Hanna S, McCoy-Simandle K, Leung E, Genna A, Condeelis J, Cox D
J Cell Sci
. 2019 Jan;
132(3).
PMID: 30659112
The interaction between tumor cells and macrophages is crucial in promoting tumor invasion and metastasis. In this study, we examined a novel mechanism of intercellular communication, namely membranous actin-based tunneling...
10.
Nobre A, Entenberg D, Wang Y, Condeelis J, Aguirre-Ghiso J
Trends Cell Biol
. 2018 Jul;
28(11):941-956.
PMID: 30041830
Hypoxia is linked to metastasis; however, how it affects metastatic progression is not clear due to limited consensus in the literature. We posit that this lack of consensus is due...