John C Whitney
Overview
Explore the profile of John C Whitney including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
50
Citations
2085
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Ahmad S, Whitney J
J Bacteriol
. 2023 Jun;
205(6):e0016123.
PMID: 37366633
S.J. Jensen, Z.C. Ruhe, A.F. Williams, D.Q. Nhan, et al. (J Bacteriol 205:e00113-23, 2023, https://doi.org/10.1128/jb.00113-23) demonstrate that a type VI secretion system (T6SS) immunity protein, Tli, functions to both neutralize...
12.
Ahmad S, Gordon I, Tsang K, Alexei A, Sychantha D, Colautti J, et al.
Proc Natl Acad Sci U S A
. 2023 Mar;
120(14):e2213771120.
PMID: 36989297
Bacteria produce a variety of nucleotide second messengers to adapt to their surroundings. Although chemically similar, the nucleotides guanosine penta- and tetraphosphate [(p)ppGpp] and adenosine penta- and tetraphosphate [(p)ppApp] have...
13.
Colautti J, Bullen N, Whitney J
Mol Microbiol
. 2022 Dec;
119(2):262-274.
PMID: 36577706
Type VI secretion systems (T6SSs) are cell envelope-spanning protein complexes that Gram-negative bacteria use to inject a diverse arsenal of antibacterial toxins into competitor cells. Recently, Wang et al. reported...
14.
Bullen N, Sychantha D, Thang S, Culviner P, Rudzite M, Ahmad S, et al.
Mol Cell
. 2022 Sep;
82(18):3484-3498.e11.
PMID: 36070765
ADP-ribosyltransferases (ARTs) were among the first identified bacterial virulence factors. Canonical ART toxins are delivered into host cells where they modify essential proteins, thereby inactivating cellular processes and promoting pathogenesis....
15.
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Klein T, Grebenc D, Shah P, McArthur O, Dickson B, Surette M, et al.
mBio
. 2022 Aug;
13(5):e0213722.
PMID: 36036513
Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial competition and virulence by secreting toxic effector proteins....
16.
Gunther P, Quentin D, Ahmad S, Sachar K, Gatsogiannis C, Whitney J, et al.
PLoS Pathog
. 2022 Jan;
18(1):e1010182.
PMID: 34986192
The type VI secretion system (T6SS) is a widespread protein export apparatus found in Gram-negative bacteria. The majority of T6SSs deliver toxic effector proteins into competitor bacteria. Yet, the structure,...
17.
Chau N, Ahmad S, Whitney J, Coombes B
PLoS Pathog
. 2021 May;
17(5):e1009532.
PMID: 33984072
Bacteria inhabit diverse environmental niches and consequently must modulate their metabolism to adapt to stress. The nucleotide second messengers guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) (collectively referred to as...
18.
Steinchen W, Ahmad S, Valentini M, Eilers K, Majkini M, Altegoer F, et al.
Mol Microbiol
. 2021 Jan;
115(6):1339-1356.
PMID: 33448498
The guanosine nucleotide-based second messengers ppGpp and pppGpp (collectively: (p)ppGpp) enable adaptation of microorganisms to environmental changes and stress conditions. In contrast, the closely related adenosine nucleotides (p)ppApp are involved...
19.
Tran H, Grebenc D, Klein T, Whitney J
Mol Microbiol
. 2021 Jan;
115(3):478-489.
PMID: 33410158
Type VII secretion systems (T7SSs) are poorly understood protein export apparatuses found in mycobacteria and many species of Gram-positive bacteria. To date, this pathway has predominantly been studied in Mycobacterium...
20.
Ahmad S, Tsang K, Sachar K, Quentin D, Tashin T, Bullen N, et al.
Elife
. 2020 Dec;
9.
PMID: 33320089
Type VI secretion systems (T6SSs) deliver antibacterial effector proteins between neighboring bacteria. Many effectors harbor N-terminal ransembrane omains (TMDs) implicated in effector translocation across target cell membranes. However, the distribution...