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John C Ralphe

Explore the profile of John C Ralphe including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 91
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Recent Articles
1.
Barton G, de Lange W, Ralphe J, Aiken J, Diffee G
Physiol Rep . 2017 Nov; 5(20). PMID: 29084842
Aging is associated with declining cardiac contractile function as well as changes in metabolism and mitochondrial function. The relationship between age-related changes in cardiac metabolism and declining cardiac contractile function...
2.
Raval K, Tao R, White B, de Lange W, Koonce C, Yu J, et al.
J Biol Chem . 2014 Dec; 290(5):3121-36. PMID: 25488666
Infantile-onset Pompe disease is an autosomal recessive disorder caused by the complete loss of lysosomal glycogen-hydrolyzing enzyme acid α-glucosidase (GAA) activity, which results in lysosomal glycogen accumulation and prominent cardiac...
3.
Clause K, Tinney J, Liu L, Gharaibeh B, Huard J, Kirk J, et al.
Tissue Eng Part C Methods . 2009 Jul; 16(3):375-85. PMID: 19601695
Skeletal muscle-derived stem cells (MDSCs) are able to differentiate into cardiomyocytes (CMs). However, it remains to be investigated whether differentiated CMs contract similar to native CMs. Here, we developed a...
4.
Momoi N, Tinney J, Liu L, Elshershari H, Hoffmann P, Ralphe J, et al.
Am J Physiol Heart Circ Physiol . 2008 Mar; 294(5):H2248-56. PMID: 18359892
Caffeine consumption during pregnancy is reported to increase the risk of in utero growth restriction and spontaneous abortion. In the present study, we tested the hypothesis that modest maternal caffeine...