John C Pesko
Overview
Explore the profile of John C Pesko including associated specialties, affiliations and a list of published articles.
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5
Citations
202
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0
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Recent Articles
1.
Ciesielski K, Bouchard C, Solis I, Coffman B, Tofighi D, Pesko J
Exp Brain Res
. 2021 Aug;
239(11):3221-3242.
PMID: 34448892
Inhibitory control, the ability to suppress irrelevant thoughts or actions, is central to cognitive and social development. Protracted maturation of frontal brain networks has been reported as a major restraint...
2.
Davids M, Roberts A, Kenkre V, Wierda W, Kumar A, Kipps T, et al.
Clin Cancer Res
. 2021 Jun;
27(17):4690-4695.
PMID: 34083230
Purpose: We previously reported a 44% overall response rate (ORR) with the oral BCL-2 inhibitor venetoclax in a phase I study of relapsed/refractory non-Hodgkin lymphoma (NHL). Complete response (CR) was...
3.
Pullarkat V, Lacayo N, Jabbour E, Rubnitz J, Bajel A, Laetsch T, et al.
Cancer Discov
. 2021 Feb;
11(6):1440-1453.
PMID: 33593877
Combining venetoclax, a selective BCL2 inhibitor, with low-dose navitoclax, a BCL-X/BCL2 inhibitor, may allow targeting of both BCL2 and BCL-X without dose-limiting thrombocytopenia associated with navitoclax monotherapy. The safety and...
4.
Raz L, Bhaskar K, Weaver J, Marini S, Zhang Q, Thompson J, et al.
Neurobiol Dis
. 2018 Jul;
126:124-136.
PMID: 30010004
Background: Hypertension-induced microvascular brain injury is a major vascular contributor to cognitive impairment and dementia. We hypothesized that chronic hypoxia promotes the hyperphosphorylation of tau and cell death in an...
5.
Erhardt E, Pesko J, Prestopnik J, Thompson J, Caprihan A, Rosenberg G
J Cereb Blood Flow Metab
. 2018 Mar;
39(8):1602-1612.
PMID: 29513153
Binswanger's disease is a form of subcortical ischemic vascular disease (SIVD-BD) with extensive white matter changes. To test the hypothesis that biomarkers could improve classification of SIVD-BD, we recruited 62...