John C McDermott
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Explore the profile of John C McDermott including associated specialties, affiliations and a list of published articles.
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46
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944
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Recent Articles
1.
Kelebeev J, MacKeracher A, Miyake T, McDermott J
J Cell Sci
. 2025 Feb;
138(4).
PMID: 39898439
Characterization of protein-protein interactions (PPIs) is a fundamental goal in the post-genomic era. Here, we document a generally applicable approach to identify cellular protein interactomes using a combination of nanobody-based...
2.
Miyake T, McDermott J
Nucleic Acids Res
. 2024 Jun;
52(14):e66.
PMID: 38932691
Transcription factors (TFs) form homo- or hetero-dimeric DNA binding complexes along with associated co-regulators that can have transcriptional repressor or activator functions. Defining the specific composition of the complexes is...
3.
Steiman S, Miyake T, McDermott J
Mol Cell Biol
. 2024 Mar;
44(2):57-71.
PMID: 38483114
Myocyte enhancer factor 2 (MEF2) proteins are involved in multiple developmental, physiological, and pathological processes in vertebrates. Protein-protein interactions underlie the plethora of biological processes impacted by MEF2A, necessitating a...
4.
Moustafa A, Hashemi S, Brar G, Grigull J, Ng S, Williams D, et al.
Cell Death Dis
. 2023 Apr;
14(4):240.
PMID: 37019881
Transcriptional regulators encoded by the Myocyte Enhancer Factor 2 (MEF2) gene family play a fundamental role in cardiac development, homeostasis and pathology. Previous studies indicate that MEF2A protein-protein interactions serve...
5.
Miyake T, McDermott J
J Cell Sci
. 2023 Feb;
136(4).
PMID: 36727534
Myogenesis, the process of muscle differentiation, requires an extensive remodeling of the cellular transcriptome and proteome. Whereas the transcriptional program underpinning myogenesis is well characterized, the required adaptation in protein...
6.
Holder E, Alibhai F, Caudle S, McDermott J, Tobin S
Am J Physiol Heart Circ Physiol
. 2022 Aug;
323(4):H609-H627.
PMID: 35960634
Cardiac cachexia is a catabolic muscle-wasting syndrome observed in approximately 1 in 10 patients with heart failure. Increased skeletal muscle atrophy leads to frailty and limits mobility, which impacts quality...
7.
Cornwell J, McDermott J
Trends Cardiovasc Med
. 2022 Jan;
33(4):204-212.
PMID: 35026393
Hypertension is a globally prevalent pathological condition and an underlying risk factor for the development of cardiac hypertrophy leading to heart failure. Myocyte enhancer factor 2 (Mef2) has been identified...
8.
Tripathi S, Miyake T, Kelebeev J, McDermott J
J Cell Sci
. 2021 Dec;
135(1).
PMID: 34859820
Hippo signaling in Drosophila and mammals is prominent in regulating cell proliferation, death and differentiation. Hippo signaling effectors (YAP and TAZ; also known as YAP1 and WWTR1, respectively) exhibit crosstalk...
9.
Miyake T, McDermott J
FEBS J
. 2021 Sep;
289(3):748-765.
PMID: 34499807
Nucleoli are well defined for their function in ribosome biogenesis, but only a small fraction of the nucleolar proteome has been characterized. Here, we report that the proto-oncogene, c-Jun, is...
10.
Paul R, Vazirani R, McDermott J, Kliewer M
AJR Am J Roentgenol
. 2021 May;
217(1):164-171.
PMID: 33978451
The purpose of the present study was to identify the subset of a wide range of serial Doppler, laboratory, and clinical parameters most predictive (both individually and in combination) of...