» Authors » John C Marioni

John C Marioni

Explore the profile of John C Marioni including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 163
Citations 21132
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Barnes J, Yoshida M, He P, Worlock K, Lindeboom R, Suo C, et al.
Sci Immunol . 2023 Dec; 8(90):eadf9988. PMID: 38100545
Studies of human lung development have focused on epithelial and mesenchymal cell types and function, but much less is known about the developing lung immune cells, even though the airways...
12.
Zhang B, He P, Lawrence J, Wang S, Tuck E, Williams B, et al.
Nature . 2023 Dec; 635(8039):668-678. PMID: 38057666
Human limbs emerge during the fourth post-conception week as mesenchymal buds, which develop into fully formed limbs over the subsequent months. This process is orchestrated by numerous temporally and spatially...
13.
Yayon N, Kedlian V, Boehme L, Suo C, Wachter B, Beuschel R, et al.
bioRxiv . 2023 Nov; PMID: 37986877
T cells develop from circulating precursors, which enter the thymus and migrate throughout specialised sub-compartments to support maturation and selection. This process starts already in early fetal development and is...
14.
Imaz-Rosshandler I, Rode C, Guibentif C, Harland L, Ton M, Dhapola P, et al.
Development . 2023 Nov; 151(3). PMID: 37982461
Early organogenesis represents a key step in animal development, during which pluripotent cells diversify to initiate organ formation. Here, we sampled 300,000 single-cell transcriptomes from mouse embryos between E8.5 and...
15.
Richard A, Ma C, Marioni J, Griffiths G
EMBO Rep . 2023 Oct; 24(11):e57653. PMID: 37860838
Effector cytotoxic T lymphocytes (CTLs) are critical for ridding the body of infected or cancerous cells. CTL T cell receptor (TCR) ligation not only drives the delivery and release of...
16.
Dann E, Cujba A, Oliver A, Meyer K, Teichmann S, Marioni J
Nat Genet . 2023 Oct; 55(11):1998-2008. PMID: 37828140
Joint analysis of single-cell genomics data from diseased tissues and a healthy reference can reveal altered cell states. We investigate whether integrated collections of data from healthy individuals (cell atlases)...
17.
Wang R, Yang X, Chen J, Zhang L, Griffiths J, Cui G, et al.
Nat Commun . 2023 Sep; 14(1):5675. PMID: 37709743
Understanding of the molecular drivers of lineage diversification and tissue patterning during primary germ layer development requires in-depth knowledge of the dynamic molecular trajectories of cell lineages across a series...
18.
Hamel R, Peruzzotti-Jametti L, Ridley K, Testa V, Yu B, Rowitch D, et al.
Heliyon . 2023 Aug; 9(8):e18339. PMID: 37636454
Traumatic spinal cord injuries (SCI) are a group of highly debilitating pathologies affecting thousands annually, and adversely affecting quality of life. Currently, no fully restorative therapies exist, and SCI still...
19.
Fleming S, Chaffin M, Arduini A, Akkad A, Banks E, Marioni J, et al.
Nat Methods . 2023 Aug; 20(9):1323-1335. PMID: 37550580
Droplet-based single-cell assays, including single-cell RNA sequencing (scRNA-seq), single-nucleus RNA sequencing (snRNA-seq) and cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq), generate considerable background noise counts, the hallmark of...
20.
Ibarra-Soria X, Thierion E, Mok G, Munsterberg A, Odom D, Marioni J
Dev Cell . 2023 Jul; 58(19):1983-1995.e7. PMID: 37499658
The mammalian body plan is shaped by rhythmic segmentation of mesoderm into somites, which are transient embryonic structures that form down each side of the neural tube. We have analyzed...