John Bartels
Overview
Explore the profile of John Bartels including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
540
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Recent Articles
1.
Mathew S, Bartels J, Banerjee I, Vodovotz Y
J Theor Biol
. 2014 Jun;
358:132-48.
PMID: 24909493
The precise inflammatory role of the cytokine interleukin (IL)-6 and its utility as a biomarker or therapeutic target have been the source of much debate, presumably due to the complex...
2.
Namas R, Bartels J, Hoffman R, Barclay D, Billiar T, Zamora R, et al.
PLoS One
. 2013 Jul;
8(7):e67419.
PMID: 23844008
We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2...
3.
An G, Bartels J, Vodovotz Y
Drug Dev Res
. 2011 May;
72(2):187-200.
PMID: 21552346
The clinical translation of promising basic biomedical findings, whether derived from reductionist studies in academic laboratories or as the product of extensive high-throughput and -content screens in the biotechnology and...
4.
Vodovotz Y, Constantine G, Faeder J, Mi Q, Rubin J, Bartels J, et al.
Immunopharmacol Immunotoxicol
. 2010 Feb;
32(2):181-95.
PMID: 20170421
Inflammation is a complex, non-linear process central to many of the diseases that affect both developed and emerging nations. A systems-based understanding of inflammation, coupled to translational applications, is therefore...
5.
Torres A, Bentley T, Bartels J, Sarkar J, Barclay D, Namas R, et al.
Shock
. 2008 Nov;
32(2):172-8.
PMID: 19008782
Hemorrhagic shock (HS) elicits a global acute inflammatory response, organ dysfunction, and death. We have used mathematical modeling of inflammation and tissue damage/dysfunction to gain insight into this complex response...
6.
Vodovotz Y, Csete M, Bartels J, Chang S, An G
PLoS Comput Biol
. 2008 Apr;
4(4):e1000014.
PMID: 18437239
Inflammation is a complex, multi-scale biologic response to stress that is also required for repair and regeneration after injury. Despite the repository of detailed data about the cellular and molecular...
7.
Vodovotz Y, Clermont G, Hunt C, Lefering R, Bartels J, Seydel R, et al.
J Crit Care
. 2007 Mar;
22(1):77-84.
PMID: 17371750
Introduction: Given the complexity of biological systems, understanding their dynamic behaviors, such as the Acute Inflammatory Response (AIR), requires a formal synthetic process. Dynamic Mathematical Modeling (DMM) represents a suite...
8.
Lagoa C, Bartels J, Baratt A, Tseng G, Clermont G, Fink M, et al.
Shock
. 2006 Nov;
26(6):592-600.
PMID: 17117135
Trauma and hemorrhagic shock (HS) elicit severe physiological disturbances that predispose the victims to subsequent organ dysfunction and death. The general lack of effective therapeutic options for these patients is...
9.
Prince J, Levy R, Bartels J, Baratt A, Kane 3rd J, Lagoa C, et al.
Mol Med
. 2006 Sep;
12(4-6):88-96.
PMID: 16953560
The inflammatory phenotype of genetically modified mice is complex, and the role of Gram-negative lipopolysaccharide (LPS) in acute inflammation induced by surgical cannulation trauma, alone or in combination with hemorrhage...
10.
Vodovotz Y, Chow C, Bartels J, Lagoa C, Prince J, Levy R, et al.
Shock
. 2006 Aug;
26(3):235-44.
PMID: 16912648
Trauma and hemorrhagic shock elicit an acute inflammatory response, predisposing patients to sepsis, organ dysfunction, and death. Few approved therapies exist for these acute inflammatory states, mainly due to the...