Johannes M Herrmann
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Explore the profile of Johannes M Herrmann including associated specialties, affiliations and a list of published articles.
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Articles
162
Citations
4675
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Recent Articles
1.
Kaushik P, Herrmann J, Hansen K
Biol Chem
. 2025 Jan;
PMID: 39828945
Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into mitochondria. If the rate of protein synthesis exceeds the capacity of the mitochondrial import machinery, precursor proteins can...
2.
Herrmann J, Lenhard S, Hansen K
Methods Enzymol
. 2024 Oct;
706:391-405.
PMID: 39455226
Mitochondria import hundreds of different precursor proteins from the cytosol and direct each of these to its specific mitochondrial subcompartment. The import routes and mechanisms by which precursors are transported...
3.
Jung F, Rodl S, Herrmann J, Muhlhaus T
Methods Enzymol
. 2024 Oct;
706:263-283.
PMID: 39455219
Mitochondria consist of several hundreds of proteins, the vast majority of which are synthesized in the cytosol as precursor proteins from where they are targeted to and imported into mitochondria....
4.
Herrmann J
FEBS Open Bio
. 2024 Oct;
14(10):1588-1590.
PMID: 39367527
Mitochondria are essential organelles of eukaryotic cells. They consist of hundreds of proteins, which are synthesized in the cytosol and imported into mitochondria via different targeting routes. In addition, a...
5.
Bohnert M, Gatsogiannis C, Herrmann J
Trends Cell Biol
. 2024 Aug;
34(9):698-699.
PMID: 39089957
The accumulation of translocation intermediates in the mitochondrial import machinery threatens cellular fitness and is associated with cancer and neurodegeneration. A recent study by Weidberg and colleagues identifies ATAD1 as...
6.
Pines O, Horwitz M, Herrmann J
FEBS J
. 2024 Jun;
291(24):5379-5393.
PMID: 38857249
Almost all mitochondrial proteins are encoded by nuclear genes and synthesized in the cytosol as precursor proteins. Signals in the amino acid sequence of these precursors ensure their targeting and...
7.
Kizmaz B, Nutz A, Egeler A, Herrmann J
FEBS Open Bio
. 2024 Apr;
14(10):1627-1639.
PMID: 38664330
The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they...
8.
Koch C, Lenhard S, Raschle M, Prescianotto-Baschong C, Spang A, Herrmann J
EMBO Rep
. 2024 Apr;
25(4):2071-2096.
PMID: 38565738
Most mitochondrial proteins are synthesized on cytosolic ribosomes and imported into mitochondria in a post-translational reaction. Mitochondrial precursor proteins which use the ER-SURF pathway employ the surface of the endoplasmic...
9.
Bertgen L, Bokenkamp J, Schneckmann T, Koch C, Raschle M, Storchova Z, et al.
Cell Rep
. 2024 Mar;
43(4):114018.
PMID: 38551959
Mitochondria consist of hundreds of proteins, most of which are inaccessible to the proteasomal quality control system of the cytosol. How cells stabilize the mitochondrial proteome during challenging conditions remains...
10.
Zannini F, Herrmann J, Couturier J, Rouhier N
Antioxidants (Basel)
. 2023 Nov;
12(11).
PMID: 38001802
Protein import and oxidative folding within the intermembrane space (IMS) of mitochondria relies on the MIA40-ERV1 couple. The MIA40 oxidoreductase usually performs substrate recognition and oxidation and is then regenerated...