Johannes D Clausen
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Explore the profile of Johannes D Clausen including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Clausen T, Nielsen O, Clausen J, Pedersen T, Hayward L
J Gen Physiol
. 2011 Jun;
138(1):117-30.
PMID: 21708955
In patients with hyperkalemic periodic paralysis (HyperKPP), attacks of muscle weakness or paralysis are triggered by K(+) ingestion or rest after exercise. Force can be restored by muscle work or...
12.
Clausen J, McIntosh D, Woolley D, Andersen J
J Biol Chem
. 2011 Feb;
286(13):11792-802.
PMID: 21288896
The mechanism of ATP modulation of E2P dephosphorylation of sarcoplasmic reticulum Ca(2+)-ATPase wild type and mutant forms was examined in nucleotide binding studies of states analogous to the various intermediates...
13.
Cardi D, Pozza A, Arnou B, Marchal E, Clausen J, Andersen J, et al.
J Biol Chem
. 2010 Jun;
285(34):26406-16.
PMID: 20530490
The antimalarial drugs artemisinins have been described as inhibiting Ca(2+)-ATPase activity of PfATP6 (Plasmodium falciparum ATP6) after expression in Xenopus oocytes. Mutation of an amino acid residue in mammalian SERCA1...
14.
Clausen J, Andersen J
J Biol Chem
. 2010 Apr;
285(27):20780-92.
PMID: 20421308
The roles of Ser(72), Glu(90), and Lys(297) at the luminal ends of transmembrane helices M1, M2, and M4 of sarcoplasmic reticulum Ca(2+)-ATPase were examined by transient and steady-state kinetic analysis...
15.
Clausen J, McIntosh D, Woolley D, Andersen J
J Biol Chem
. 2008 Oct;
283(51):35703-14.
PMID: 18930923
ATP plays dual roles in the reaction cycle of the sarcoplasmic reticulum Ca2+-ATPase by acting as the phosphorylating substrate as well as in nonphosphorylating (modulatory) modes accelerating conformational transitions of...
16.
Marchand A, Lund Winther A, Holm P, Olesen C, Montigny C, Arnou B, et al.
J Biol Chem
. 2008 Mar;
283(21):14867-82.
PMID: 18356161
In recent years crystal structures of the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), stabilized in various conformations with nucleotide and phosphate analogs, have been obtained. However, structural analysis of mutant forms would...
17.
Clausen J, McIntosh D, Anthonisen A, Woolley D, Vilsen B, Andersen J
J Biol Chem
. 2007 May;
282(28):20686-97.
PMID: 17504757
ATP binds to sarcoplasmic reticulum Ca(2+)-ATPase both in a phosphorylating (catalytic) mode and in a nonphosphorylating (modulatory) mode, the latter leading to acceleration of phosphoenzyme turnover (Ca(2)E(1)P --> E(2)P and...
18.
Anthonisen A, Clausen J, Andersen J
J Biol Chem
. 2006 Aug;
281(42):31572-82.
PMID: 16893884
Crystal structures have shown that the conserved TGES loop of the Ca2+-ATPase is isolated in the Ca2E1 state but becomes inserted in the catalytic site in E2 states. Here, we...
19.
Clausen J, McIntosh D, Woolley D, Anthonisen A, Vilsen B, Andersen J
J Biol Chem
. 2006 Feb;
281(14):9471-81.
PMID: 16449230
Mutants with alteration to Asn(706) of the highly conserved (701)TGDGVND(707) motif in domain P of sarcoplasmic reticulum Ca(2+)-ATPase were analyzed for changes in transport cycle kinetics and binding of the...
20.
Dally S, Bredoux R, Corvazier E, Andersen J, Clausen J, Dode L, et al.
Biochem J
. 2006 Jan;
395(2):249-58.
PMID: 16402920
We recently documented the expression of a novel human mRNA variant encoding a yet uncharacterized SERCA [SR (sarcoplasmic reticulum)/ER (endoplasmic reticulum) Ca2+-ATPase] protein, SERCA2c [Gélébart, Martin, Enouf and Papp (2003)...