Johanna A Jorgensen
Overview
Explore the profile of Johanna A Jorgensen including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1022
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Recent Articles
1.
Sellers A, van Beek S, Hashim D, Baak R, Pallubinsky H, Moonen-Kornips E, et al.
Nat Metab
. 2024 Dec;
6(12):2246-2253.
PMID: 39643644
Cold acclimation increases insulin sensitivity, and some level of muscle contraction appears to be needed for provoking this effect. Here 15 men and (postmenopausal) women with overweight or obesity, the...
2.
Harmsen J, Kotte M, Habets I, Bosschee F, Frenken K, Jorgensen J, et al.
J Physiol
. 2023 Dec;
602(23):6417-6433.
PMID: 38051503
Twenty-four hour rhythmicity in whole-body substrate metabolism, skeletal muscle clock gene expression and mitochondrial respiration is compromised upon insulin resistance. With exercise training known to ameliorate insulin resistance, our objective...
3.
de Wit-Verheggen V, Schrauwen-Hinderling V, Brouwers K, Jorgensen J, Schaart G, Gemmink A, et al.
Sci Rep
. 2023 May;
13(1):8346.
PMID: 37221197
Cardiac energy status, measured as phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio with 31P-Magnetic Resonance Spectroscopy (31P-MRS) in vivo, is a prognostic factor in heart failure and is lowered in cardiometabolic disease....
4.
Gemmink A, Daemen S, Wefers J, Hansen J, van Moorsel D, Astuti P, et al.
Mol Metab
. 2023 Apr;
72:101727.
PMID: 37062525
Mitochondrial network dynamics may play role in metabolic homeostasis. Whether mitochondrial network dynamics are involved in adaptations to day-night fluctuations in energy supply and demand is unclear. Here we visualized...
5.
van Beek S, Bruls Y, Vanweert F, Fealy C, Connell N, Schaart G, et al.
Nat Commun
. 2023 Jan;
14(1):173.
PMID: 36635304
β-agonist treatment improves skeletal muscle glucose uptake and whole-body glucose homeostasis in rodents, likely via mTORC2-mediated signalling. However, human data on this topic is virtually absent. We here investigate the...
6.
Veelen A, Andriessen C, Op den Kamp Y, Erazo-Tapia E, de Ligt M, Mevenkamp J, et al.
Metabolism
. 2023 Jan;
140:155396.
PMID: 36592688
Aims/hypothesis: Sodium-glucose cotransporter 2 inhibitor (SGLT2i) treatment in type 2 diabetes mellitus patients results in glucosuria, causing an energy loss, and triggers beneficial metabolic adaptations. It is so far unknown...
7.
Op den Kamp Y, Gemmink A, de Ligt M, Dautzenberg B, Kornips E, Jorgensen J, et al.
Mol Metab
. 2022 Oct;
66:101620.
PMID: 36280113
Objective: SGLT2 inhibitors increase urinary glucose excretion and have beneficial effects on cardiovascular and renal outcomes; the underlying mechanism may be metabolic adaptations due to urinary glucose loss. Here, we...
8.
Remie C, Janssens G, Bilet L, van Weeghel M, Duvivier B, de Wit V, et al.
Diabetologia
. 2021 Sep;
64(12):2817-2828.
PMID: 34510226
Aims/hypothesis: In our current society sedentary behaviour predominates in most people and is associated with the risk of developing type 2 diabetes. It has been suggested that replacing sitting time...
9.
Nascimento E, Moonen M, Remie C, Gariani K, Jorgensen J, Schaart G, et al.
J Clin Endocrinol Metab
. 2021 Feb;
106(5):1437-1447.
PMID: 33524145
Context: Elevating nicotinamide adenine dinucleotide (NAD+) levels systemically improves metabolic health, which can be accomplished via nicotinamide riboside (NR). Previously, it was demonstrated that NR supplementation in high-fat-diet (HFD)-fed mice...
10.
Houzelle A, Jorgensen J, Schaart G, Daemen S, van Polanen N, Fealy C, et al.
Diabetologia
. 2020 Dec;
64(2):424-436.
PMID: 33258025
Aims/hypothesis: Mitochondria operate in networks, adapting to external stresses and changes in cellular metabolic demand and are subject to various quality control mechanisms. On the basis of these traits, we...