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Johann Rohrl

Explore the profile of Johann Rohrl including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 315
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Recent Articles
1.
Pique-Borras M, Rohrl J, Kunstle G
Neurogastroenterol Motil . 2024 Sep; 37(1):e14924. PMID: 39344827
Background: Impaired gastric accommodation is one of the most frequent symptoms of functional dyspepsia. The safety and efficacy of conventional treatments remain to be proven and alternative herbal therapies have...
2.
Rohrl J, Pique-Borras M, Jaklin M, Werner M, Werz O, Josef H, et al.
Plants (Basel) . 2023 Mar; 12(6). PMID: 36987036
is well known for its anti-inflammatory properties. While the anti-inflammatory activity of Arnica flowers (Arnicae flos) has been extensively studied, that of the whole plant (Arnicae planta tota) is less...
3.
Barabas N, Rohrl J, Holler E, Hehlgans T
Immunobiology . 2013 Jan; 218(7):1005-11. PMID: 23332217
Our previous studies indicated that mouse beta defensin 14 (mBD14, Defb14), a newly identified member of the beta-defensin super family, interacts with the chemokine receptors CCR2 and CCR6. In this...
4.
Rohrl J, Geissler E, Hehlgans T
Oncoimmunology . 2012 Nov; 1(7):1159-1160. PMID: 23170263
For many years, β-defensins were best known for their antimicrobial activity. However, β-defensins also exert immunomodulatory functions, such as the chemotactic recruitment of immune cells via chemokine receptors. We demonstrated...
5.
Rohrl J, Huber B, Koehl G, Geissler E, Hehlgans T
J Immunol . 2012 Apr; 188(10):4931-9. PMID: 22504651
β-Defensins are known for their antimicrobial activity and belong to the molecular barrier of the innate immune system against invading pathogens. In addition, it has been shown that some members...
6.
Wimmer N, Huber B, Wege A, Barabas N, Rohrl J, Pfeffer K, et al.
Mol Immunol . 2012 Mar; 51(2):128-35. PMID: 22437076
Our previous studies indicated that LTβR activation mainly by T cell derived LTα₁β₂ is crucial for the control and down-regulation of intestinal inflammation. In order to dissect the cellular and...
7.
Moehrlen U, Lechner A, Baumel M, Dostert K, Rohrl J, Meuli M, et al.
Pediatr Surg Int . 2012 Mar; 28(5):507-13. PMID: 22426493
Purpose: There is evidence that open as well as minimally invasive abdominal surgery impair post-operative innate and acquired immune function. To compare the impact of these approaches as well as...
8.
Wimmer N, Huber B, Barabas N, Rohrl J, Pfeffer K, Hehlgans T
J Immunol . 2012 Feb; 188(7):3426-33. PMID: 22357629
Our previous studies indicated that lymphotoxin β receptor (LTβR) activation controls and downregulates inflammatory reactions. In this study, we report that LTβR activation on primary mouse macrophages results in induction...
9.
Rohrl J, Yang D, Oppenheim J, Hehlgans T
J Immunol . 2010 May; 184(12):6688-94. PMID: 20483750
Beta-defensins play a dual role during immune response. Their direct antimicrobial properties contribute to the local innate immune response by combating microbial invasions. Furthermore, previous studies revealed the capacity of...
10.
Daller B, Musch W, Rohrl J, Tumanov A, Nedospasov S, Mannel D, et al.
Int J Cancer . 2010 May; 128(6):1363-70. PMID: 20473944
Lymphotoxin beta receptor (LTβR) activation on mouse fibrosarcoma cells (BFS-1) results in enhanced solid tumor growth paralleled by increased angiogenesis induced by the expression of pro-angiogenic CXCL2. In our study,...