Johan Heldin
Overview
Explore the profile of Johan Heldin including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
217
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Recent Articles
1.
Olsson F, Wahlen E, Heldin J, Soderberg O, Norlin M, Lennartsson J
Biochem Biophys Res Commun
. 2024 Oct;
736:150866.
PMID: 39447276
This study explored the signaling interplay between the vitamin D receptor (VDR) and receptor tyrosine kinases (RTKs). Epidermal growth factor (EGF) and platelet-derived growth factor (PDGF)-BB promotes cell proliferation in...
2.
Rubin Sander M, Tsiatsiou A, Wang K, Papadopoulos N, Rorsman C, Olsson F, et al.
Growth Factors
. 2024 Oct;
42(4):147-160.
PMID: 39387439
Platelet-derived growth factor (PDGF)-induced signalling via PDGF receptor β (PDGFRβ) leads to activation of downstream signalling pathways which regulate multiple cellular responses. It is unclear how PDGFRβ is degraded; both...
3.
Wahlen E, Lennartsson J, Heldin J
Biochem Biophys Rep
. 2024 Oct;
40:101828.
PMID: 39380576
This study investigates the role of Rho GTPases, specifically Cdc42, Rac1, and RhoA, in platelet-derived growth factor receptors (PDGFRα and PDGFRβ) signaling. Signal transducer and activator of transcription (STAT) proteins,...
4.
Wenson L, Leino M, Jarvius M, Heldin J, Koos B, Soderberg O
Expert Rev Proteomics
. 2024 Feb;
21(1-3):65-80.
PMID: 38363709
Introduction: Development of new methods is essential to make great leaps in science, opening up new avenues for research, but the process behind method development is seldom described. Areas Covered:...
5.
Bivehed E, Hellman B, Wenson L, Stenerlow B, Soderberg O, Heldin J
Nucleic Acids Res
. 2024 Jan;
52(4):e22.
PMID: 38261985
In the comet assay, tails are formed after single-cell gel electrophoresis if the cells have been exposed to genotoxic agents. These tails include a mixture of both DNA single-strand breaks...
6.
Raykova D, Kermpatsou D, Malmqvist T, Harrison P, Rubin Sander M, Stiller C, et al.
Nat Commun
. 2023 Sep;
14(1):5450.
PMID: 37673885
No abstract available.
7.
Wahlen E, Olsson F, Raykova D, Soderberg O, Heldin J, Lennartsson J
Biochem Biophys Res Commun
. 2023 May;
665:195-201.
PMID: 37163940
The interplay between membrane subregions and receptor tyrosine kinases (RTK) will influence signaling in both normal and pathological RTK conditions. In this study, epidermal growth factor receptor (EGFR) and platelet-derived...
8.
Ternet C, Junk P, Sevrin T, Catozzi S, Wahlen E, Heldin J, et al.
Life Sci Alliance
. 2023 Mar;
6(5).
PMID: 36894174
Ras is a key switch controlling cell behavior. In the GTP-bound form, Ras interacts with numerous effectors in a mutually exclusive manner, where individual Ras-effectors are likely part of larger...
9.
Raykova D, Kermpatsou D, Malmqvist T, Harrison P, Rubin Sander M, Stiller C, et al.
Nat Commun
. 2022 Aug;
13(1):4755.
PMID: 35963857
Determining the levels of protein-protein interactions is essential for the analysis of signaling within the cell, characterization of mutation effects, protein function and activation in health and disease, among others....
10.
Wahlen E, Olsson F, Soderberg O, Lennartsson J, Heldin J
Cell Signal
. 2022 Jul;
98:110411.
PMID: 35878489
No abstract available.