Joerg Striessnig
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Explore the profile of Joerg Striessnig including associated specialties, affiliations and a list of published articles.
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23
Citations
2293
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Recent Articles
1.
Giang N, Mars M, Moreau M, Mejia J, Bouchaud G, Magnan A, et al.
Allergy
. 2021 Jun;
77(2):525-539.
PMID: 34181765
Background: Voltage-gated calcium (Ca 1) channels contribute to T-lymphocyte activation. Ca 1.2 and Ca 1.3 channels are expressed in Th2 cells but their respective roles are unknown, which is investigated...
2.
Benkert J, Hess S, Roy S, Beccano-Kelly D, Wiederspohn N, Duda J, et al.
Nat Commun
. 2019 Nov;
10(1):5094.
PMID: 31704946
Degeneration of dopaminergic neurons in the substantia nigra causes the motor symptoms of Parkinson's disease. The mechanisms underlying this age-dependent and region-selective neurodegeneration remain unclear. Here we identify Cav2.3 channels...
3.
Toyoda F, Mesirca P, Dubel S, Ding W, Striessnig J, Mangoni M, et al.
Sci Rep
. 2017 Aug;
7(1):7869.
PMID: 28801600
The spontaneous activity of sinoatrial node (SAN) pacemaker cells is generated by a functional interplay between the activity of ionic currents of the plasma membrane and intracellular Ca dynamics. The...
4.
Tan G, Negro G, Pinggera A, Tizen Laim N, Mohamed Rose I, Ceral J, et al.
Hypertension
. 2017 Jun;
70(1):129-136.
PMID: 28584016
Mutations in , , , , and are thought to cause the excessive autonomous aldosterone secretion of aldosterone-producing adenomas (APAs). The histopathology of mutant APAs, the most common and largest,...
5.
Mesirca P, Bidaud I, Briec F, Evain S, Torrente A, Le Quang K, et al.
Proc Natl Acad Sci U S A
. 2016 Feb;
113(7):E932-41.
PMID: 26831068
Dysfunction of pacemaker activity in the sinoatrial node (SAN) underlies "sick sinus" syndrome (SSS), a common clinical condition characterized by abnormally low heart rate (bradycardia). If untreated, SSS carries potentially...
6.
Torrente A, Mesirca P, Neco P, Rizzetto R, Dubel S, Barrere C, et al.
Cardiovasc Res
. 2016 Jan;
109(3):451-61.
PMID: 26786159
Aims: Sino-atrial node (SAN) automaticity is an essential mechanism of heart rate generation that is still not completely understood. Recent studies highlighted the importance of intracellular Ca(2+) ([Ca(2+)]i) dynamics during...
7.
Poetschke C, Dragicevic E, Duda J, Benkert J, Dougalis A, DeZio R, et al.
Sci Rep
. 2015 Sep;
5:13688.
PMID: 26381090
The preferential degeneration of Substantia nigra dopamine midbrain neurons (SN DA) causes the motor-symptoms of Parkinson's disease (PD). Voltage-gated L-type calcium channels (LTCCs), especially the Cav1.3-subtype, generate an activity-related oscillatory...
8.
Zamponi G, Striessnig J, Koschak A, Dolphin A
Pharmacol Rev
. 2015 Sep;
67(4):821-70.
PMID: 26362469
Voltage-gated calcium channels are required for many key functions in the body. In this review, the different subtypes of voltage-gated calcium channels are described and their physiologic roles and pharmacology...
9.
Gstir R, Schafferer S, Scheideler M, Misslinger M, Griehl M, Daschil N, et al.
RNA
. 2014 Oct;
20(12):1929-43.
PMID: 25344396
We have generated a novel, neuro-specific ncRNA microarray, covering 1472 ncRNA species, to investigate their expression in different mouse models for central nervous system diseases. Thereby, we analyzed ncRNA expression...
10.
Dragicevic E, Poetschke C, Duda J, Schlaudraff F, Lammel S, Schiemann J, et al.
Brain
. 2014 Jun;
137(Pt 8):2287-302.
PMID: 24934288
Dopamine midbrain neurons within the substantia nigra are particularly prone to degeneration in Parkinson's disease. Their selective loss causes the major motor symptoms of Parkinson's disease, but the causes for...