Christina Poetschke
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Explore the profile of Christina Poetschke including associated specialties, affiliations and a list of published articles.
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7
Citations
197
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Recent Articles
1.
Siller A, Hofer N, Tomagra G, Burkert N, Hess S, Benkert J, et al.
Elife
. 2022 Jul;
11.
PMID: 35792082
In dopaminergic (DA) (SN) neurons Cav2.3 R-type Ca-currents contribute to somatodendritic Ca-oscillations. This activity may contribute to the selective degeneration of these neurons in Parkinson's disease (PD) since Cav2.3-knockout is...
2.
Mannal N, Kleiner K, Fauler M, Dougalis A, Poetschke C, Liss B
Front Synaptic Neurosci
. 2021 Mar;
13:635050.
PMID: 33716704
Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark...
3.
Simons C, Benkert J, Deuter N, Poetschke C, Pongs O, Schneider T, et al.
Front Mol Neurosci
. 2019 Dec;
12:252.
PMID: 31827421
Neuronal Ca sensor proteins (NCS) transduce changes in Ca homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration...
4.
Benkert J, Hess S, Roy S, Beccano-Kelly D, Wiederspohn N, Duda J, et al.
Nat Commun
. 2019 Nov;
10(1):5094.
PMID: 31704946
Degeneration of dopaminergic neurons in the substantia nigra causes the motor symptoms of Parkinson's disease. The mechanisms underlying this age-dependent and region-selective neurodegeneration remain unclear. Here we identify Cav2.3 channels...
5.
Poetschke C, Dragicevic E, Duda J, Benkert J, Dougalis A, DeZio R, et al.
Sci Rep
. 2015 Sep;
5:13688.
PMID: 26381090
The preferential degeneration of Substantia nigra dopamine midbrain neurons (SN DA) causes the motor-symptoms of Parkinson's disease (PD). Voltage-gated L-type calcium channels (LTCCs), especially the Cav1.3-subtype, generate an activity-related oscillatory...
6.
Krabbe S, Duda J, Schiemann J, Poetschke C, Schneider G, Kandel E, et al.
Proc Natl Acad Sci U S A
. 2015 Feb;
112(12):E1498-506.
PMID: 25675529
There is strong evidence that the core deficits of schizophrenia result from dysfunction of the dopamine (DA) system, but details of this dysfunction remain unclear. We previously reported a model...
7.
Dragicevic E, Poetschke C, Duda J, Schlaudraff F, Lammel S, Schiemann J, et al.
Brain
. 2014 Jun;
137(Pt 8):2287-302.
PMID: 24934288
Dopamine midbrain neurons within the substantia nigra are particularly prone to degeneration in Parkinson's disease. Their selective loss causes the major motor symptoms of Parkinson's disease, but the causes for...