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Joel R Steele

Explore the profile of Joel R Steele including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 96
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Recent Articles
11.
Strange N, Luu L, Ong V, Wee B, Phillips M, McCaughey L, et al.
J Bacteriol . 2024 Mar; 206(4):e0037123. PMID: 38445896
Importance: is an important obligate intracellular pathogen that has a unique biphasic developmental cycle. HtrA is an essential stress or virulence protease in many bacteria, with many different functions. Previously,...
12.
Koehn L, Steele J, Schittenhelm R, Turner B, Nicolazzo J
Mol Pharm . 2024 Feb; 21(4):1756-1767. PMID: 38415587
Amyotrophic lateral sclerosis (ALS) is characterized by death and dysfunction of motor neurons that result in a rapidly progressing loss of motor function. While there are some data on alterations...
13.
Landen S, Jacques M, Hiam D, Alvarez-Romero J, Schittenhelm R, Shah A, et al.
Biol Sex Differ . 2023 Sep; 14(1):56. PMID: 37670389
Background: Exercise training elicits changes in muscle physiology, epigenomics, transcriptomics, and proteomics, with males and females exhibiting differing physiological responses to exercise training. However, the molecular mechanisms contributing to the...
14.
Zhang H, Steele J, Valipour Kahrood H, Deveson Lucas D, Shah A, Schittenhelm R
J Proteome Res . 2023 Aug; 22(9):2890-2899. PMID: 37584946
Phosphoproteomics is nowadays the method of choice to comprehensively identify and quantify thousands of phosphorylated peptides and their associated proteins with the goal of interrogating changes in signal transduction pathways...
15.
Chaaya R, Steele J, Oliver B, Chen H, Machaalani R
J Chem Neuroanat . 2023 Jun; 132:102303. PMID: 37343645
The use of e-cigarettes/e-vapour, and the consumption of a high-fat diet (HFD), are two popular lifestyle choices associated with alterations in the hippocampus. This study, using a mouse model, investigated...
16.
Lim Kam Sian T, Goncalves G, Steele J, Shamekhi T, Bramberger L, Jin D, et al.
Front Immunol . 2023 Jun; 14:1107576. PMID: 37334365
Human leukocyte antigen (HLA) molecules play a crucial role in directing adaptive immune responses based on the nature of their peptide ligands, collectively coined the immunopeptidome. As such, the study...
17.
Chang Y, Lupton C, Bayly-Jones C, Keen A, DAndrea L, Lucato C, et al.
Nat Struct Mol Biol . 2022 Jul; 29(8):767-773. PMID: 35864164
P-Rex (PI(3,4,5)P-dependent Rac exchanger) guanine nucleotide exchange factors potently activate Rho GTPases. P-Rex guanine nucleotide exchange factors are autoinhibited, synergistically activated by Gβγ and PI(3,4,5)P binding and dysregulated in cancer....
18.
Steele J, Italiano C, Phillips C, Violi J, Pu L, Rodgers K, et al.
Proteomes . 2022 Jun; 10(2). PMID: 35736802
In the original publication, there was a mistake in Table 2 as published [...].
19.
Prakash A, Taylor L, Varkey M, Hoxie N, Mohammed Y, Goo Y, et al.
Cancers (Basel) . 2021 Oct; 13(20). PMID: 34680183
The Clinical Proteomic Tumor Analysis Consortium (CPTAC) has provided some of the most in-depth analyses of the phenotypes of human tumors ever constructed. Today, the majority of proteomic data analysis...
20.
Quinn A, Phillips C, Violi J, Steele J, Johnson M, Westerhausen M, et al.
Amino Acids . 2021 Jul; 53(9):1351-1359. PMID: 34283312
The cyanobacterial non-protein amino acid α-amino-β-methylaminopropionic acid, more commonly known as BMAA, was first discovered in the seeds of the ancient gymnosperm Cycad circinalis (now Cycas micronesica Hill). BMAA was...