Joel R Steele
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Explore the profile of Joel R Steele including associated specialties, affiliations and a list of published articles.
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27
Citations
96
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Recent Articles
1.
Wise A, Krisnadevi I, Bruell S, Lee H, Bhuvan T, Kassianos A, et al.
Kidney Int Rep
. 2025 Feb;
10(2):535-548.
PMID: 39990892
Introduction: Fabry disease (FD) results from pathogenic variants, leading to a deficiency in lysosomal α-galactosidase A (α-Gal A) and accumulation of the sphingolipid globotriaosylceramide (Gb3). This leads to severe renal...
2.
Yang C, Camargo Tavares L, Lee H, Steele J, Ribeiro R, Beale A, et al.
Gut Microbes
. 2024 Dec;
17(1):2441356.
PMID: 39709554
The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk...
3.
Bayly-Jones C, Lupton C, DAndrea L, Chang Y, Jones G, Steele J, et al.
Sci Adv
. 2024 Nov;
10(47):eadr5807.
PMID: 39565846
Tuberous sclerosis complex (TSC) is targeted to the lysosomal membrane, where it hydrolyzes RAS homolog-mTORC1 binding (RHEB) from its GTP-bound to GDP-bound state, inhibiting mechanistic target of rapamycin complex 1...
4.
Hayes B, Harper M, Venugopal H, Lewis J, Wright A, Lee H, et al.
Nat Commun
. 2024 Oct;
15(1):8709.
PMID: 39379370
The type VI secretion system (T6SS) is a molecular machine utilised by many Gram-negative bacteria to deliver antibacterial toxins into adjacent cells. Here we present the structure of Tse15, a...
5.
Hsiao Y, Zhang H, Li G, Deng Y, Yu F, Valipour Kahrood H, et al.
J Proteome Res
. 2024 Sep;
23(10):4303-4315.
PMID: 39254081
The FragPipe computational proteomics platform is gaining widespread popularity among the proteomics research community because of its fast processing speed and user-friendly graphical interface. Although FragPipe produces well-formatted output tables...
6.
Costacurta M, Sandow J, Maher B, Susanto O, Vervoort S, Devlin J, et al.
FEBS J
. 2024 Jul;
291(22):4892-4912.
PMID: 38975872
Immunomodulatory imide drugs (IMiDs) are central components of therapy for multiple myeloma (MM). IMiDs bind cereblon (CRBN), an adaptor for the CUL4-DDB1-RBX1 E3 ligase to change its substrate specificity and...
7.
Le L, Steele J, Ying L, Schittenhelm R, Ferrero R
J Extracell Biol
. 2024 Jun;
2(5):e84.
PMID: 38938280
Contaminants within cell culture media often co-isolate with eukaryotic extracellular vesicles (EVs) thus affecting their biological properties. It has yet to be investigated if this is also true for bacterial...
8.
Timpani C, Debrincat D, Kourakis S, Boyer R, Formosa L, Steele J, et al.
FASEB J
. 2024 Jun;
38(11):e23718.
PMID: 38847487
Female carriers of a Duchenne muscular dystrophy (DMD) gene mutation manifest exercise intolerance and metabolic anomalies that may be exacerbated following menopause due to the loss of estrogen, a known...
9.
Lim Kam Sian T, Sun C, Cain J, Steele J, Hanchapola I, Stoychev S, et al.
Methods Mol Biol
. 2024 Apr;
2806:229-242.
PMID: 38676807
Genomic profiling has identified therapeutic targets for precision treatment of certain cancers, but many patients lack actionable mutations. Additional omics approaches, like proteomics and phosphoproteomics, are essential for comprehensive mapping...
10.
Hsiao Y, Zhang H, Li G, Deng Y, Yu F, Valipour Kahrood H, et al.
bioRxiv
. 2024 Mar;
PMID: 38496650
The FragPipe computational proteomics platform is gaining widespread popularity among the proteomics research community because of its fast processing speed and user-friendly graphical interface. Although FragPipe produces well-formatted output tables...