Joel Hirschhorn
Overview
Explore the profile of Joel Hirschhorn including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
2276
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Recent Articles
1.
Richard D, Muthuirulan P, Young M, Yengo L, Vedantam S, Marouli E, et al.
Cell
. 2024 Nov;
188(1):15-32.e24.
PMID: 39549696
Underlying variation in height are regulatory changes to chondrocytes, cartilage cells comprising long-bone growth plates. Currently, we lack knowledge on epigenetic regulation and gene expression of chondrocytes sampled across the...
2.
Kennedy C, Doyle R, Gough O, Mcevoy C, Anallen S, McAnallen S, et al.
Kidney360
. 2024 Oct;
5(12):1799-1812.
PMID: 39450948
No abstract available.
3.
Fleur R, Tanofsky-Kraff M, Yanovski J, Horton N, Reich L, Chavarro J, et al.
Res Sq
. 2024 Apr;
PMID: 38562761
Objectives: We investigated whether empirically derived childhood obesity phenotypes were differentially associated with risk of hypertension in young adulthood, and whether these associations differed by sex. Methods: Data came from...
4.
Hawkes G, Yengo L, Vedantam S, Marouli E, Beaumont R, Tyrrell J, et al.
PLoS Genet
. 2023 Sep;
19(9):e1010934.
PMID: 37733769
Findings from genome-wide association studies have facilitated the generation of genetic predictors for many common human phenotypes. Stratifying individuals misaligned to a genetic predictor based on common variants may be...
5.
Lennon N, Kottyan L, Kachulis C, Abul-Husn N, Arias J, Belbin G, et al.
medRxiv
. 2023 Jun;
PMID: 37333246
Polygenic risk scores (PRS) have improved in predictive performance supporting their use in clinical practice. Reduced predictive performance of PRS in diverse populations can exacerbate existing health disparities. The NHGRI-funded...
6.
Hawkes G, Yengo L, Vedantam S, Marouli E, Beaumont R, Tyrrell J, et al.
bioRxiv
. 2023 Feb;
PMID: 36798175
Author Summary: Human genetics is becoming increasingly useful to help predict human traits across a population owing to findings from large-scale genetic association studies and advances in the power of...
7.
Abman S, Armstrong S, Baker S, Bogue C, Carlo W, Chalak L, et al.
Pediatr Res
. 2021 Aug;
91(1):264.
PMID: 34389800
No abstract available.
8.
Abman S, Armstrong S, Baker S, Bogue C, Carlo W, Chalak L, et al.
Pediatr Res
. 2020 Sep;
91(1):72.
PMID: 32882704
No abstract available.
9.
Agha G, Mendelson M, Ward-Caviness C, Joehanes R, Huan T, Gondalia R, et al.
Circulation
. 2019 Aug;
140(8):645-657.
PMID: 31424985
Background: DNA methylation is implicated in coronary heart disease (CHD), but current evidence is based on small, cross-sectional studies. We examined blood DNA methylation in relation to incident CHD across...
10.
Sohail M, Maier R, Ganna A, Bloemendal A, Martin A, Turchin M, et al.
Elife
. 2019 Mar;
8.
PMID: 30895926
Editorial Note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is...