Brian E Henderson
Overview
Explore the profile of Brian E Henderson including associated specialties, affiliations and a list of published articles.
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358
Citations
22665
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Recent Articles
1.
Goodrich J, Singer-Berk M, Son R, Sveden A, Wood J, England E, et al.
Nat Commun
. 2021 Jun;
12(1):3505.
PMID: 34108472
Hundreds of thousands of genetic variants have been reported to cause severe monogenic diseases, but the probability that a variant carrier develops the disease (termed penetrance) is unknown for virtually...
2.
Graff M, Justice A, Young K, Marouli E, Zhang X, Fine R, et al.
Am J Hum Genet
. 2021 Mar;
108(4):564-582.
PMID: 33713608
Although many loci have been associated with height in European ancestry populations, very few have been identified in African ancestry individuals. Furthermore, many of the known loci have yet to...
3.
Flannick J, Mercader J, Fuchsberger C, Udler M, Mahajan A, Wessel J, et al.
Nature
. 2019 May;
570(7759):71-76.
PMID: 31118516
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and 24,440 ...
4.
Schumacher F, Olama A, Berndt S, Benlloch S, Ahmed M, Saunders E, et al.
Nat Genet
. 2019 Jan;
51(2):363.
PMID: 30622367
In the version of this article initially published, the name of author Manuela Gago-Dominguez was misspelled as Manuela Gago Dominguez. The error has been corrected in the HTML and PDF...
5.
Dadaev T, Saunders E, Newcombe P, Anokian E, Leongamornlert D, Brook M, et al.
Nat Commun
. 2018 Jun;
9(1):2256.
PMID: 29892050
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian...
6.
Schumacher F, Olama A, Berndt S, Benlloch S, Ahmed M, Saunders E, et al.
Nat Genet
. 2018 Jun;
50(7):928-936.
PMID: 29892016
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa...
7.
Ghoussaini M, Edwards S, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, et al.
Nat Commun
. 2018 Apr;
9:16193.
PMID: 29633761
This corrects the article DOI: 10.1038/ncomms5999.
8.
Conti D, Wang K, Sheng X, Bensen J, Hazelett D, Cook M, et al.
J Natl Cancer Inst
. 2017 Nov;
109(8).
PMID: 29117387
Prostate cancer incidence is 1.6-fold higher in African Americans than in other populations. The risk factors that drive this disparity are unknown and potentially consist of social, environmental, and genetic...
9.
Mercader J, Liao R, Bell A, Dymek Z, Estrada K, Tukiainen T, et al.
Diabetes
. 2017 Aug;
66(11):2903-2914.
PMID: 28838971
Type 2 diabetes (T2D) affects more than 415 million people worldwide, and its costs to the health care system continue to rise. To identify common or rare genetic variation with...
10.
Lindstrom S, Ablorh A, Chapman B, Gusev A, Chen G, Turman C, et al.
Breast Cancer Res
. 2016 Nov;
18(1):109.
PMID: 27814745
Background: Although genome-wide association studies (GWASs) have identified thousands of disease susceptibility regions, the underlying causal mechanism in these regions is not fully known. It is likely that the GWAS...