Joel F Schildbach
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Explore the profile of Joel F Schildbach including associated specialties, affiliations and a list of published articles.
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31
Citations
538
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Recent Articles
1.
Cox K, Schildbach J
Plasmid
. 2017 Apr;
91:53-60.
PMID: 28359666
The R1 antibiotic resistance plasmid, originally discovered in a clinical Salmonella isolate in London, 1963, has served for decades as a key model for understanding conjugative plasmids. Despite its scientific...
2.
Gruber C, Lang S, Rajendra V, Nuk M, Raffl S, Schildbach J, et al.
Front Mol Biosci
. 2016 Aug;
3:32.
PMID: 27486582
Bacterial conjugation is a form of type IV secretion used to transport protein and DNA directly to recipient bacteria. The process is cell contact-dependent, yet the mechanisms enabling extracellular events...
3.
Completing the specificity swap: Single-stranded DNA recognition by F and R100 TraI relaxase domains
Guja K, Schildbach J
Plasmid
. 2015 Apr;
80:1-7.
PMID: 25841886
During conjugative plasmid transfer, one plasmid strand is cleaved and transported to the recipient bacterium. For F and related plasmids, TraI contains the relaxase or nickase activity that cleaves the...
4.
Cresawn S, Pope W, Jacobs-Sera D, Bowman C, Russell D, Dedrick R, et al.
PLoS One
. 2015 Mar;
10(3):e0118725.
PMID: 25742016
Mycobacteriophages--viruses of mycobacterial hosts--are genetically diverse but morphologically are all classified in the Caudovirales with double-stranded DNA and tails. We describe here a group of five closely related mycobacteriophages--Corndog, Catdawg,...
5.
Buller A, Freeman M, Schildbach J, Townsend C
Biochemistry
. 2014 Jun;
53(26):4273-81.
PMID: 24933323
In the past decade, there have been major achievements in understanding the relationship between enzyme catalysis and protein structural plasticity. In autoprocessing systems, however, there is a sparsity of direct...
6.
Clark N, Raththagala M, Wright N, Buenger E, Schildbach J, Krueger S, et al.
J Mol Model
. 2014 Jun;
20(6):2308.
PMID: 24898939
Bacterial conjugation, a DNA transfer mechanism involving transport of one plasmid strand from donor to recipient, is driven by plasmid-encoded proteins. The F TraI protein nicks one F plasmid strand,...
7.
Hemmis C, Wright N, Majumdar A, Schildbach J
Biomol NMR Assign
. 2014 Apr;
8(2):435-8.
PMID: 24771093
TrbB from the conjugative plasmid F is a 181-residue disulfide bond isomerase that plays a role in the correct folding and maintenance of disulfide bonds within F plasmid encoded proteins...
8.
Hemmis C, Schildbach J
Plasmid
. 2013 Jun;
70(2):168-89.
PMID: 23721857
Bacterial conjugation is the process by which a conjugative plasmid transfers from donor to recipient bacterium. During this process, single-stranded plasmid DNA is actively and specifically transported from the cytoplasm...
9.
Buller A, Labonte J, Freeman M, Wright N, Schildbach J, Townsend C
J Mol Biol
. 2012 Jun;
422(4):508-18.
PMID: 22706025
cis-Autoproteolysis is a post-translational modification necessary for the function of ThnT, an enzyme involved in the biosynthesis of the β-lactam antibiotic thienamycin. This modification generates an N-terminal threonine nucleophile that...
10.
Wright N, Raththagala M, Hemmis C, Edwards S, Curtis J, Krueger S, et al.
Proteins
. 2012 May;
80(9):2250-61.
PMID: 22611034
TraI, the F plasmid-encoded nickase, is a 1756 amino acid protein essential for conjugative transfer of plasmid DNA from one bacterium to another. Although crystal structures of N- and C-terminal...