Joe Horecka
Overview
Explore the profile of Joe Horecka including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
512
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Recent Articles
1.
Li J, Kolberg K, Schlecht U, St Onge R, Aparicio A, Horecka J, et al.
J Biol Chem
. 2018 Dec;
294(4):1257-1266.
PMID: 30514758
Multidrug resistance is highly conserved in mammalian, fungal, and bacterial cells, is characterized by resistance to several unrelated xenobiotics, and poses significant challenges to managing infections and many cancers. Eukaryotes...
2.
Roy K, Smith J, Vonesch S, Lin G, Szu Tu C, Lederer A, et al.
Nat Biotechnol
. 2018 May;
36(6):512-520.
PMID: 29734294
Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. Here we...
3.
Harvey C, Tang M, Schlecht U, Horecka J, Fischer C, Lin H, et al.
Sci Adv
. 2018 Apr;
4(4):eaar5459.
PMID: 29651464
For decades, fungi have been a source of U.S. Food and Drug Administration-approved natural products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in DNA sequencing suggest that millions...
4.
Jalili R, Horecka J, Swartz J, Davis R, Persson H
Proc Natl Acad Sci U S A
. 2018 Jan;
115(5):E925-E933.
PMID: 29339495
Proximity ligation assay (PLA) is a powerful tool for quantitative detection of protein biomarkers in biological fluids and tissues. Here, we present the circular proximity ligation assay (c-PLA), a highly...
5.
Billingsley J, DeNicola A, Barber J, Tang M, Horecka J, Chu A, et al.
Metab Eng
. 2017 Sep;
44:117-125.
PMID: 28939278
Monoterpene indole alkaloids (MIAs) represent a structurally diverse, medicinally essential class of plant derived natural products. The universal MIA building block strictosidine was recently produced in the yeast Saccharomyces cerevisiae,...
6.
Smith J, Schlecht U, Xu W, Suresh S, Horecka J, Proctor M, et al.
Mol Syst Biol
. 2017 Feb;
13(2):913.
PMID: 28193641
The low costs of array-synthesized oligonucleotide libraries are empowering rapid advances in quantitative and synthetic biology. However, high synthesis error rates, uneven representation, and lack of access to individual oligonucleotides...
7.
Xie B, Horecka J, Chu A, Davis R, Becker E, Primig M
RNA Biol
. 2016 Jul;
13(9):772-82.
PMID: 27362276
The origin of replication complex subunit ORC1 is important for DNA replication. The gene is known to encode a meiotic transcript isoform (mORC1) with an extended 5'-untranslated region (5'-UTR), which...
8.
Charter N, Horecka J, Loh C, Doan A, Wehrman T, Olson K
Methods Mol Biol
. 2015 Jul;
1314:51-61.
PMID: 26139254
Alternative, antibody-free techniques to western analysis of protein blots can offer reduced assay times for routine analysis of expression of recombinant proteins. We have adapted the commercially available enzyme fragment...
9.
Becker E, Liu Y, Lardenois A, Walther T, Horecka J, Stuparevic I, et al.
J Proteomics
. 2015 Feb;
119:30-44.
PMID: 25662576
Biological Significance: Our integrated genomics study provides insight into the interplay between the transcriptome and the proteome in diploid yeast cells undergoing vegetative growth in the presence of glucose (fermentation)...
10.
Lardenois A, Stuparevic I, Liu Y, Law M, Becker E, Smagulova F, et al.
Nucleic Acids Res
. 2014 Dec;
43(1):115-28.
PMID: 25477386
It was recently reported that the sizes of many mRNAs change when budding yeast cells exit mitosis and enter the meiotic differentiation pathway. These differences were attributed to length variations...