Jobst Landgrebe
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Explore the profile of Jobst Landgrebe including associated specialties, affiliations and a list of published articles.
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9
Citations
203
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Recent Articles
1.
von der Heyde S, Raman N, Gabelia N, Matias-Guiu X, Yoshino T, Tsukada Y, et al.
Cell Death Dis
. 2024 Sep;
15(9):691.
PMID: 39327466
Tumor tissue collections are used to uncover pathways associated with disease outcomes that can also serve as targets for cancer treatment, ideally by comparing the molecular properties of cancer tissues...
2.
Schneede A, Schmidt C, Holtta-Vuori M, Heeren J, Willenborg M, Blanz J, et al.
J Cell Mol Med
. 2009 Nov;
15(2):280-95.
PMID: 19929948
The mechanisms of endosomal and lysosomal cholesterol traffic are still poorly understood. We showed previously that unesterified cholesterol accumulates in the late endosomes and lysosomes of fibroblasts deficient in both...
3.
Stypmann J, Janssen P, Prestle J, Engelen M, Kogler H, Lullmann-Rauch R, et al.
Basic Res Cardiol
. 2006 Apr;
101(4):281-91.
PMID: 16604439
Objective: Mutations in the highly glycosylated lysosome associated membrane protein-2 (LAMP-2) cause, as recently shown, familial Danon disease with mental retardation, mild myopathy and fatal cardiomyopathy. Extent and basis of...
4.
Horvay K, Claussen M, Katzer M, Landgrebe J, Pieler T
Dev Biol
. 2006 Feb;
291(1):1-11.
PMID: 16448642
Germ plasm formation is considered to define the first step in germ cell development. Xenopus Dead end represents a germ plasm specific transcript that is homologous to the previously characterized...
5.
Willenborg M, Schmidt C, Braun P, Landgrebe J, von Figura K, Saftig P, et al.
J Lipid Res
. 2005 Sep;
46(12):2559-69.
PMID: 16177447
Niemann-Pick disease type C (NPC), caused by mutations in the NPC1 gene or the NPC2 gene, is characterized by the accumulation of unesterified cholesterol and other lipids in endo/lysosomal compartments....
6.
Schlott T, Eiffert H, Bohne W, Landgrebe J, Brunner E, Spielbauer B, et al.
Gynecol Oncol
. 2005 Jul;
98(3):409-19.
PMID: 16005053
Objectives: The obligate intracellular bacterium Chlamydia trachomatis is frequently found in association with benign proliferative, pre-neoplastic and malignant changes in cervical epithelium. The present study addresses the possible role of...
7.
Landgrebe J, Bretz F, Brunner E
In Silico Biol
. 2004 Oct;
4(4):461-70.
PMID: 15506995
In the last years, biostatistical research has begun to apply linear models and design theory to develop efficient experimental designs and analysis tools for gene expression microarray data. With two-colour...
8.
Landgrebe J, Dierks T, Schmidt B, von Figura K
Gene
. 2003 Oct;
316:47-56.
PMID: 14563551
Recently, the human C(alpha)-formylglycine (FGly)-generating enzyme (FGE), whose deficiency causes the autosomal-recessively transmitted lysosomal storage disease multiple sulfatase deficiency (MSD), has been identified. In sulfatases, FGE posttranslationally converts a cysteine...
9.
Landgrebe J, Wurst W, Welzl G
Genome Biol
. 2002 May;
3(4):RESEARCH0019.
PMID: 11983060
Background: In microarray data analysis, the comparison of gene-expression profiles with respect to different conditions and the selection of biologically interesting genes are crucial tasks. Multivariate statistical methods have been...