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Jan-Bernd Stukenborg

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Articles 59
Citations 999
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Recent Articles
1.
He W, Luo Q, Zhao J, Wang M, Zhao A, Feng L, et al.
Adv Sci (Weinh) . 2025 Feb; :e2410533. PMID: 39996497
Klinefelter syndrome (KS), characterized by the presence of at least one extra X-chromosome, is a common cause of male infertility. However, the mechanism underlying the failure of germline specification is...
2.
Kearney E, Greenald D, Matilionyte G, Lane S, Tharmalingam M, Davies J, et al.
Reprod Fertil . 2025 Jan; 6(1). PMID: 39836027
Abstract: Methods to quantify germ cell number in human immature testicular tissues are essential to evaluate the impact of chemotherapy exposures and to optimise cryopreservation protocols used in fertility preservation...
3.
Embaie B, Sarkar H, Alchahin A, Alchahin A, Otte J, Olsen T, et al.
Cancer Res . 2025 Jan; 85(6):1015-1034. PMID: 39808065
Transgenic mice and organoid models, such as three-dimensional tumoroid cultures, have emerged as powerful tools for investigating cancer development and targeted therapies. Yet, the extent to which these preclinical models...
4.
Cui Y, Harteveld F, Ba Omar H, Yang Y, Bjarnason R, Romerius P, et al.
Hum Reprod Open . 2024 Aug; 2024(3):hoae049. PMID: 39188568
Study Question: Can human pre- and peri-pubertal testicular cells obtained from childhood cancer patients, previously treated with chemotherapy, form testicular organoids (TOs)? Summary Answer: Organoid formation from testicular tissue collected...
5.
Lahtinen A, Funke M, Krallmann C, Wyrwoll M, Jarisch A, Yang Y, et al.
Br J Haematol . 2024 May; 205(1):229-235. PMID: 38810989
This study examines spermatogonial numbers in testicular samples from 43 prepubertal patients undergoing haematopoietic stem cell transplantation (HSCT). High-dose chemotherapy and/or radiation during HSCT can impact spermatogenesis requiring fertility preservation....
6.
Duffin K, Neuhaus N, Andersen C, Barraud-Lange V, Braye A, Eguizabal C, et al.
Hum Reprod Open . 2024 Mar; 2024(2):hoae010. PMID: 38449521
Study Question: Twenty years after the inception of the first fertility preservation programme for pre-pubertal boys, what are the current international practices with regard to cryopreservation of immature testicular tissue?...
7.
Wamaitha S, Nie X, Pandolfi E, Wang X, Yang Y, Stukenborg J, et al.
Dev Cell . 2023 Aug; 58(20):2097-2111.e3. PMID: 37582368
Formation of either an ovary or a testis during human embryonic life is one of the most important sex-specific events leading to the emergence of secondary sexual characteristics and sex...
8.
Elfageih R, Reda A, Kjartansdottir K, Pampanini V, Soder O, Stukenborg J
Reprod Fertil . 2023 May; PMID: 37186557
Objective: Testicular samples obtained for fertility preservation often need to be transported between clinics. This study aimed to mimic this short-term hypothermic storage (4-8 °C) and explore the impact of...
9.
Jain V, Chuva de Sousa Lopes S, Benotmane M, Verratti V, Mitchell R, Stukenborg J
NPJ Microgravity . 2023 Mar; 9(1):24. PMID: 36973260
This review summarises key aspects of the first reproductive and developmental systems Science Community White Paper, supported by the European Space Agency (ESA). Current knowledge regarding human development and reproduction...
10.