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Joao C Silva

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Articles 37
Citations 312
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Recent Articles
1.
Munoz-Galan H, Enshaei H, Silva J, Esteves T, Ferreira F, Casanovas J, et al.
ACS Appl Polym Mater . 2025 Jan; 6(14):8093-8104. PMID: 39839886
Diabetes is a metabolic disorder caused by the body's inability to produce or use insulin. Considering the figures projected by the World Health Organization, research on insulin therapy is crucial....
2.
Santos M, Silva J, Carvalho M
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201249
The periodontium is a complex hierarchical structure composed of alveolar bone, periodontal ligament, cementum, and gingiva. Periodontitis is an inflammatory disease that damages and destroys the periodontal tissues supporting the...
3.
Gonella S, Domingues M, Miguel F, Moura C, Rodrigues C, Ferreira F, et al.
Gels . 2024 Jul; 10(7). PMID: 39057446
Functional articular cartilage regeneration remains an unmet medical challenge, increasing the interest for innovative biomaterial-based tissue engineering (TE) strategies. Hydrogels, 3D macromolecular networks with hydrophilic groups, present articular cartilage-like features...
4.
Silva J, Meneses J, Garrudo F, Fernandes S, Alves N, Ferreira F, et al.
Sci Rep . 2024 Mar; 14(1):5458. PMID: 38443455
Electrical stimulation (ES) has been described as a promising tool for bone tissue engineering, being known to promote vital cellular processes such as cell proliferation, migration, and differentiation. Despite the...
5.
Silva J, Marcelino P, Meneses J, Barbosa F, Moura C, Marques A, et al.
J Mater Chem B . 2024 Feb; 12(11):2771-2794. PMID: 38384239
In this work, we propose a simple, reliable, and versatile strategy to create 3D electroconductive scaffolds suitable for bone tissue engineering (TE) applications with electrical stimulation (ES). The proposed scaffolds...
6.
Meneses J, Fernandes S, Silva J, Ferreira F, Alves N, Pascoal-Faria P
Front Bioeng Biotechnol . 2024 Jan; 11:1308096. PMID: 38162184
Bioreactors have been employed in tissue engineering to sustain longer and larger cell cultures, managing nutrient transfer and waste removal. Multiple designs have been developed, integrating sensor and stimulation technologies...
7.
Costa C, Cruz C, Pinho T, Torres S, Silva J, Madureira J, et al.
Cardiol Young . 2023 Nov; 34(4):865-869. PMID: 37921218
Background And Aim: Pulmonary regurgitation is the most common complication in repaired tetralogy of Fallot patients. Severe chronic pulmonary regurgitation can be tolerated for decades, but if not treated, it...
8.
Barbosa F, Garrudo F, Marques A, Cabral J, Morgado J, Ferreira F, et al.
Int J Mol Sci . 2023 Sep; 24(17). PMID: 37686010
Bone defect repair remains a critical challenge in current orthopedic clinical practice, as the available therapeutic strategies only offer suboptimal outcomes. Therefore, bone tissue engineering (BTE) approaches, involving the development...
9.
Barbosa F, Garrudo F, Alberte P, Resina L, Carvalho M, Jain A, et al.
Sci Technol Adv Mater . 2023 Aug; 24(1):2242242. PMID: 37638280
Osteoporotic-related fractures are among the leading causes of chronic disease morbidity in Europe and in the US. While a significant percentage of fractures can be repaired naturally, in delayed-union and...
10.
Garrudo F, Filippone G, Resina L, Silva J, Barbosa F, Ferreira L, et al.
Polymers (Basel) . 2023 Jul; 15(13). PMID: 37447406
This study describes, for the first time, the successful incorporation of poly(ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) in Poly(acrylonitrile) (PAN) fibers. While electroconductive PEDOT:PSS is extremely challenging to electrospun into fibers. Therefore, PAN,...