Joanna Izabela Lachowicz
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Explore the profile of Joanna Izabela Lachowicz including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Poulson B, Szczepski K, Lachowicz J, Jaremko L, Emwas A, Jaremko M
RSC Adv
. 2022 May;
10(1):215-227.
PMID: 35492549
The process of aggregation of proteins and peptides is dependent on the concentration of proteins, and the rate of aggregation can be altered by the presence of metal ions, but...
12.
Emwas A, Szczepski K, Al-Younis I, Lachowicz J, Jaremko M
Front Pharmacol
. 2022 Apr;
13:805782.
PMID: 35387341
Fluxomics is an innovative -omics research field that measures the rates of all intracellular fluxes in the central metabolism of biological systems. Fluxomics gathers data from multiple different -omics fields,...
13.
Dhahri M, Alghrably M, Mohammed H, Badshah S, Noreen N, Mouffouk F, et al.
Pharmaceutics
. 2022 Jan;
14(1).
PMID: 35056897
Neurodegenerative diseases are a serious and widespread global public health burden amongst aging populations. The total estimated worldwide global cost of dementia was US$818 billion in 2015 and has been...
14.
Lachowicz J, Lecca L, Meloni F, Campagna M
Molecules
. 2021 Nov;
26(21).
PMID: 34771058
An increasing number of pathologies correlates with both toxic and essential metal ions dyshomeostasis. Next to known genetic disorders (e.g., Wilson's Disease and β-Thalassemia) other pathological states such as neurodegeneration...
15.
Coni P, Pichiri G, Lachowicz J, Ravarino A, Ledda F, Fanni D, et al.
Molecules
. 2021 Nov;
26(21).
PMID: 34771023
Zinc is the second most abundant trace element in the human body, and it plays a fundamental role in human physiology, being an integral component of hundreds of enzymes and...
16.
Abdelrahman S, Alghrably M, Campagna M, Hauser C, Jaremko M, Lachowicz J
Molecules
. 2021 Aug;
26(16).
PMID: 34443319
Metformin has been used for decades in millions of type 2 diabetes mellitus patients. In this time, correlations between metformin use and the occurrence of other disorders have been noted,...
17.
Emwas A, Alghrably M, Dhahri M, Sharfalddin A, Alsiary R, Jaremko M, et al.
Ageing Res Rev
. 2021 Jun;
70:101391.
PMID: 34119687
Conformational diseases are caused by the aggregation of misfolded proteins. The risk for such pathologies develops years before clinical symptoms appear, and is higher in people with alpha-1 antitrypsin (AAT)...
18.
Emwas A, Al-Rifai N, Szczepski K, Alsuhaymi S, Rayyan S, Almahasheer H, et al.
Foods
. 2021 Jun;
10(6).
PMID: 34072780
A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic...
19.
"What Doesn't Kill You Makes You Stronger": Future Applications of Amyloid Aggregates in Biomedicine
Abdelrahman S, Alghrably M, Lachowicz J, Emwas A, Hauser C, Jaremko M
Molecules
. 2020 Nov;
25(22).
PMID: 33187056
Amyloid proteins are linked to the pathogenesis of several diseases including Alzheimer's disease, but at the same time a range of functional amyloids are physiologically important in humans. Although the...
20.
Emwas A, Szczepski K, Poulson B, Chandra K, McKay R, Dhahri M, et al.
Molecules
. 2020 Oct;
25(20).
PMID: 33050240
Studying disease models at the molecular level is vital for drug development in order to improve treatment and prevent a wide range of human pathologies. Microbial infections are still a...