Joanna Izabela Lachowicz
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Explore the profile of Joanna Izabela Lachowicz including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Lachowicz J, Szczepski K, Scano A, Casu C, Fais S, Orru G, et al.
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33027928
Health-care systems that develop rapidly and efficiently may increase the lifespan of humans. Nevertheless, the older population is more fragile, and is at an increased risk of disease development. A...
22.
Lachowicz J, Torre G, Cappai R, Randaccio E, Nurchi V, Bachor R, et al.
Dalton Trans
. 2020 Feb;
49(9):2862-2879.
PMID: 32067003
Mimosine is a non-protein amino acid with various properties, such as antibacterial, anti-inflammatory, anti-cancer and anti-virus among others. Due to its structural similarity with deferiprone (DFP), mimosine is a potential...
23.
Berto S, Alladio E, Daniele P, Laurenti E, Bono A, Sgarlata C, et al.
Molecules
. 2019 Oct;
24(20).
PMID: 31635063
Hydroxypyrone derivatives have a good bioavailability in rats and mice and have been used in drug development. Moreover, they show chelating properties towards vanadyl cation that could be used in...
24.
Al-Harthi S, Lachowicz J, Nowakowski M, Jaremko M, Jaremko L
J Inorg Biochem
. 2019 Jun;
198:110716.
PMID: 31153112
Human serum albumin (HSA) is a monomeric, globular, multi-carrier and the most abundant protein in the blood. HSA displays multiple ligand binding sites with extraordinary binding capacity for a wide...
25.
Torre G, Mujika J, Lachowicz J, Ramos M, Lopez X
Dalton Trans
. 2019 Jan;
48(18):6003-6018.
PMID: 30688329
The potential neurotoxic role of Al(iii) and its proposed link with the insurgence of Alzheimer's Disease (AD) have attracted increasing interest towards the determination of the nature of bioligands that...
26.
Pilo M, Farre R, Lachowicz J, Masolo E, Panzanelli A, Sanna G, et al.
J Anal Methods Chem
. 2018 Apr;
2018:1849439.
PMID: 29686926
Enzyme-based sensors have emerged as important analytical tools with application in diverse fields, and biosensors for the detection of glucose using the enzyme glucose oxidase have been widely investigated. In...
27.
Lachowicz J, Nurchi V, Crisponi G, Jaraquemada-Pelaez M, Caltagirone C, Peana M, et al.
Eur J Pharm Sci
. 2016 Nov;
97:158-169.
PMID: 27838251
We conducted a thorough study of Cu complex formation equilibria with Irbesartan and Losartan, the two primary drugs for the cure of cardiovascular diseases, with the aim of recognising if...
28.
Lachowicz J, Nurchi V, Crisponi G, Jaraquemada-Pelaez M, Ostrowska M, Jezierska J, et al.
J Inorg Biochem
. 2015 Aug;
151:94-106.
PMID: 26281974
High stability of the complexes formed at physiological pH is one of the basic requisites that a good iron chelator must possess. At the same time the chelating agent must...
29.
Lachowicz J, Nurchi V, Crisponi G, Pelaez M, Rescigno A, Stefanowicz P, et al.
J Inorg Biochem
. 2015 Aug;
151:36-43.
PMID: 26239546
Kojic acid is a natural antifungal and antibacterial agent that has been extensively studied for its tyrosinase inhibitory and metal coordination properties. Tyrosinase is a metalloenzyme with two copper ions...
30.
Peana M, Medici S, Nurchi V, Lachowicz J, Crisponi G, Crespo-Alonso M, et al.
J Inorg Biochem
. 2015 Feb;
148:69-77.
PMID: 25687185
Here we report about the complex formation among an amine-bearing bis-kojic acid, 6,6'-(2-(diethylamino)ethylazanediyl)bis(methylene)bis(5-hydroxy-2-hydroxymethyl-4H-pyran-4-one) and two metal ions, the trivalent hard and not essential metal ion Al(III) and the borderline and...