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Joan Mannick

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Articles 11
Citations 255
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Recent Articles
1.
Kritchevsky S, Zamora E, Bhasin S, Cohen A, Chandler A, Covinsky K, et al.
Res Sq . 2025 Feb; PMID: 39989956
Using a modified Delphi process, we engaged 28 experts in clinical trials, geriatrics, and research translation to determine if there were consensus around what clinical endpoints should be used for...
2.
Lyu Y, Fu Q, Wilczok D, Ying K, King A, Antebi A, et al.
Aging (Albany NY) . 2024 Oct; 16(20):12955-12976. PMID: 39418098
The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We,...
3.
Wyles S, Mehta R, Mannick J, Day D
J Cosmet Dermatol . 2024 Jul; 23(9):2814-2815. PMID: 39030745
No abstract available.
4.
Moqri M, Herzog C, Poganik J, Justice J, Belsky D, Higgins-Chen A, et al.
Cell . 2023 Sep; 186(18):3758-3775. PMID: 37657418
With the rapid expansion of aging biology research, the identification and evaluation of longevity interventions in humans have become key goals of this field. Biomarkers of aging are critically important...
5.
Rolland Y, Sierra F, Ferrucci L, Barzilai N, de Cabo R, Mannick J, et al.
Nat Commun . 2023 Aug; 14(1):5038. PMID: 37598227
Geroscience is becoming a major hope for preventing age-related diseases and loss of function by targeting biological mechanisms of aging. This unprecedented paradigm shift requires optimizing the design of future...
6.
Boekstein N, Barzilai N, Bertram A, Betts-LaCroix J, Fortney K, Helliwell S, et al.
Nat Biotechnol . 2023 Jun; 41(8):1053-1055. PMID: 37365260
No abstract available.
7.
PrabhuDas M, Fuldner R, Farber D, Kuchel G, Mannick J, Nikolich-Zugich J, et al.
Nat Aging . 2023 Mar; 1(12):1073-1077. PMID: 36908301
On 16 and 17 March 2021, the National Institute of Allergy and Infectious Diseases and the National Institute of Aging convened a virtual workshop to discuss developments in SARS-CoV-2 research...
8.
Reynolds J, Posina K, Zhu L, Jenkins T, Matto F, Hausladen A, et al.
Proc Natl Acad Sci U S A . 2023 Feb; 120(9):e2220769120. PMID: 36812211
S-Nitrosohemoglobin (SNO-Hb) is unique among vasodilators in coupling blood flow to tissue oxygen requirements, thus fulfilling an essential function of the microcirculation. However, this essential physiology has not been tested...
9.
DeVito L, Barzilai N, Cuervo A, Niedernhofer L, Milman S, Levine M, et al.
Ann N Y Acad Sci . 2021 Sep; 1507(1):70-83. PMID: 34498278
For many years, it was believed that the aging process was inevitable and that age-related diseases could not be prevented or reversed. The geroscience hypothesis, however, posits that aging is,...
10.
Armanios M, de Cabo R, Mannick J, Partridge L, van Deursen J, Villeda S
Nat Med . 2015 Dec; 21(12):1395-9. PMID: 26646495
Aging is a risk factor for several of the world's most prevalent diseases, including neurodegenerative disorders, cancer, cardiovascular disease and metabolic disease. Although our understanding of the molecular pathways that...