Joachim Morschhauser
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Explore the profile of Joachim Morschhauser including associated specialties, affiliations and a list of published articles.
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119
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4140
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Recent Articles
1.
Barker K, Santana D, Zhang Q, Peters T, Rybak J, Morschhauser J, et al.
bioRxiv
. 2025 Feb;
PMID: 39990401
Objective: Candida auris has emerged as a fungal pathogen of particular concern owing in part to its propensity to exhibit antifungal resistance, especially to the commonly prescribed antifungal fluconazole. In...
2.
Morschhauser J
PLoS Pathog
. 2024 Nov;
20(11):e1012643.
PMID: 39495716
The yeast Candida albicans is usually a harmless member of the normal microbiota in healthy persons but is also a major fungal pathogen that can colonize and infect almost every...
3.
Ramirez-Zavala B, Hoffmann A, Kruger I, Schwanfelder S, Barker K, Rogers P, et al.
mSphere
. 2024 Jun;
9(7):e0038824.
PMID: 38940507
Importance: is one of the medically most important fungi and a model organism to study fungal pathogenicity. Investigating gene function in this diploid yeast has been facilitated by the adaptation...
4.
Ramirez-Zavala B, Kruger I, Schwanfelder S, Barker K, Rogers P, Morschhauser J
mSphere
. 2024 Jun;
9(7):e0027024.
PMID: 38860767
Importance: Transcription factors are central regulators of gene expression, and knowledge about which transcription factor regulates specific genes in response to a certain signal is important to understand the behavior...
5.
Ramirez-Zavala B, Betsova D, Schwanfelder S, Kruger I, Mottola A, Kruger T, et al.
mSphere
. 2023 Nov;
8(6):e0054623.
PMID: 38010000
The SNF1 protein kinase signaling pathway, which is highly conserved in eukaryotic cells, is important for metabolic adaptations in the pathogenic yeast . However, so far, it has remained elusive...
6.
Oneissi M, Cruz M, Ramirez-Zavala B, Lindemann-Perez E, Morschhauser J, Garsin D, et al.
PLoS Pathog
. 2023 Sep;
19(9):e1011692.
PMID: 37769015
The signals that denote mammalian host environments and dictate the activation of signaling pathways in human-associated microorganisms are often unknown. The transcription regulator Rtg1/3 in the human fungal pathogen Candida...
7.
Ramirez-Zavala B, Kruger I, Wollner A, Schwanfelder S, Morschhauser J
PLoS Genet
. 2023 Aug;
19(8):e1010890.
PMID: 37561787
Protein kinases are central components of almost all signaling pathways that control cellular activities. In the model organism Saccharomyces cerevisiae, the paralogous protein kinases Ypk1 and Ypk2, which control membrane...
8.
Raschig M, Ramirez-Zavala B, Wiest J, Saedtler M, Gutmann M, Holzgrabe U, et al.
Arch Pharm (Weinheim)
. 2022 Nov;
356(2):e2200463.
PMID: 36403201
Increasing resistance against antimycotic drugs challenges anti-infective therapies today and contributes to the mortality of infections by drug-resistant Candida species and strains. Therefore, novel antifungal agents are needed. A promising...
9.
Doorley L, Rybak J, Berkow E, Zhang Q, Morschhauser J, Rogers P
Antimicrob Agents Chemother
. 2022 Jun;
66(7):e0028922.
PMID: 35699442
Candida parapsilosis is a common cause of invasive candidiasis worldwide and is the most commonly is7olated species among pediatric and neonatal populations. Previous work has demonstrated that nonsynonymous mutations in...
10.
Brandt P, Gerwien F, Wagner L, Kruger T, Ramirez-Zavala B, Mirhakkak M, et al.
Front Cell Infect Microbiol
. 2022 May;
12:850531.
PMID: 35601106
Protein kinases play a crucial role in regulating cellular processes such as growth, proliferation, environmental adaptation and stress responses. Serine-arginine (SR) protein kinases are highly conserved in eukaryotes and regulate...