Joachim Kirsch
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Explore the profile of Joachim Kirsch including associated specialties, affiliations and a list of published articles.
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55
Citations
1036
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Recent Articles
1.
Kiss E, Kins S, Gorgas K, Venczel Szakacs K, Kirsch J, Kuhse J
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38673751
Plant-derived multitarget compounds may represent a promising therapeutic strategy for multifactorial diseases, such as Alzheimer's disease (AD). Artemisinin and its derivatives were indicated to beneficially modulate various aspects of AD...
2.
Fitzsimons L, Tasouri E, Willaredt M, Stetson D, Gojak C, Kirsch J, et al.
Dev Dyn
. 2023 Sep;
253(3):312-332.
PMID: 37776236
Introduction: Primary cilia play pivotal roles in the patterning and morphogenesis of a wide variety of organs during mammalian development. Here we examined murine foregut septation in the cobblestone mutant,...
3.
Kuhse J, Groeneweg F, Kins S, Gorgas K, Nawrotzki R, Kirsch J, et al.
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902054
Alzheimer's disease (AD) is characterized by synaptic failure and neuronal loss. Recently, we demonstrated that artemisinins restored the levels of key proteins of inhibitory GABAergic synapses in the hippocampus of...
4.
Sonmez A, Mustafa R, Ryll S, Tuorto F, Wacheul L, Ponti D, et al.
Cell Death Dis
. 2021 Dec;
12(12):1139.
PMID: 34880223
Transcriptional and cellular-stress surveillance deficits are hallmarks of Huntington's disease (HD), a fatal autosomal-dominant neurodegenerative disorder caused by a pathological expansion of CAG repeats in the Huntingtin (HTT) gene. The...
5.
Mustafa R, Rawas C, Mannal N, Kreiner G, Spittau B, Kaminska K, et al.
Antioxidants (Basel)
. 2021 Aug;
10(8).
PMID: 34439532
Primary cilia (PC) are microtubule-based protrusions of the cell membrane transducing molecular signals during brain development. Here, we report that PC are required for maintenance of Substantia nigra (SN) dopaminergic...
6.
Kiss E, Kins S, Zoller Y, Schilling S, Gorgas K, Gross D, et al.
Mol Cell Neurosci
. 2021 May;
113:103624.
PMID: 33933588
Alzheimer's disease (AD) is the most frequent form of dementia, characterized histopathologically by the formation of amyloid plaques and neurofibrillary tangles in the brain. Amyloid β-peptide (Aβ) is a major...
7.
Sumida Y, Nakamura K, Feil S, Siebold M, Kirsch J, Siebold R
Knee Surg Sports Traumatol Arthrosc
. 2021 Apr;
30(5):1535-1542.
PMID: 33891163
Purpose: To report second-look arthroscopic assessment after all-arthroscopic autologous chondrocyte implantation (ACI) for articular cartilage defects at the patella. Methods: A second-look arthroscopy after all-arthroscopic ACI using chondrospheres (ACT3D) was...
8.
Kiss E, Kins S, Gorgas K, Orlik M, Fischer C, Endres K, et al.
Biol Chem
. 2021 Apr;
403(1):73-87.
PMID: 33878252
Artemisinins, a group of plant-derived sesquiterpene lactones, are efficient antimalarial agents. They also share anti-inflammatory and anti-viral activities and were considered for treatment of neurodegenerative disorders like Alzheimer's disease (AD)....
9.
Zhou L, Kiss E, Demmig R, Kirsch J, Nawrotzki R, Kuhse J
Histochem Cell Biol
. 2021 Apr;
156(1):5-18.
PMID: 33796945
Gephyrin is a multifunctional scaffolding protein anchoring glycine- and subtypes of GABA type A- receptors at inhibitory postsynaptic membrane specializations by binding to the microtubule (MT) and/or the actin cytoskeleton....
10.
Paech D, Klopries K, Nawrotzki R, Schlemmer H, Giesel F, Kirsch J, et al.
Anat Sci Educ
. 2020 Nov;
15(1):143-154.
PMID: 33170986
Cadaver-specific postmortem computed tomography (PMCT) has become an integral part in anatomy teaching at several universities. Recently, the feasibility of contrast-enhanced (CE)-PMCT has been demonstrated. The purpose of this study...