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Jo V Rushworth

Explore the profile of Jo V Rushworth including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 619
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Recent Articles
1.
Cassambai S, Bridge H, Gill P, Shobaloju S, Sgamma T, Rushworth J
Essays Biochem . 2022 Mar; 66(1):29-37. PMID: 35294007
More inclusive, authentic assessments are required to address awarding gaps and to ensure that bioscience students can apply their knowledge to relevant work-based scenarios. In this case report, we present...
2.
Kotecha A, Correa A, Fisher K, Rushworth J
Biosensors (Basel) . 2018 Apr; 8(2). PMID: 29652815
Cases of Alzheimer's disease (AD) are rising exponentially due to increasing global life expectancy. There are approximately 50 million sufferers worldwide, with prevalence rising most rapidly in low-income countries such...
3.
Jarosz-Griffiths H, Noble E, Rushworth J, Hooper N
J Biol Chem . 2016 Jan; 291(7):3174-83. PMID: 26719327
Several different receptor proteins have been identified that bind monomeric, oligomeric, or fibrillar forms of amyloid-β (Aβ). "Good" receptors internalize Aβ or promote its transcytosis out of the brain, whereas...
4.
Tiernan J, Ingram N, Marston G, Perry S, Rushworth J, Coletta P, et al.
Nanomedicine (Lond) . 2015 Feb; 10(8):1223-31. PMID: 25694062
Fluorescent imaging of colorectal tumor cells would improve tumor localization and allow intra-operative staging, facilitating stratification of surgical resections thereby improving patient outcomes. We aimed to develop and test fluorescent...
5.
Ahmed A, Rushworth J, Hirst N, Millner P
Clin Microbiol Rev . 2014 Jul; 27(3):631-46. PMID: 24982325
Bacterial pathogens are important targets for detection and identification in medicine, food safety, public health, and security. Bacterial infection is a common cause of morbidity and mortality worldwide. In spite...
6.
Rushworth J, Ahmed A, Griffiths H, Pollock N, Hooper N, Millner P
Biosens Bioelectron . 2014 Feb; 56:83-90. PMID: 24480125
Alzheimer's disease (AD) is the most common form of dementia, with over 37 million sufferers worldwide and a global cost of over $600 billion. There is currently no cure for...
7.
Ahmed A, Rushworth J, Wright J, Millner P
Anal Chem . 2013 Nov; 85(24):12118-25. PMID: 24256123
Streptococcus pyogenes , also known as group A streptococcus (GAS), is a Gram positive human pathogen responsible for invasive and noninvasive human infections with a high incidence rate. Traditional detection...
8.
Rushworth J, Griffiths H, Watt N, Hooper N
J Biol Chem . 2013 Feb; 288(13):8935-51. PMID: 23386614
Soluble oligomers of the amyloid-β (Aβ) peptide cause neurotoxicity, synaptic dysfunction, and memory impairments that underlie Alzheimer disease (AD). The cellular prion protein (PrP(C)) was recently identified as a high...
9.
Watt N, Taylor D, Kerrigan T, Griffiths H, Rushworth J, Whitehouse I, et al.
Nat Commun . 2012 Oct; 3:1134. PMID: 23072804
Zinc is released into the synaptic cleft upon exocytotic stimuli, although the mechanism for its reuptake into neurons is unresolved. Here we show that the cellular prion protein enhances the...
10.
Rushworth J, Hooper N
Int J Alzheimers Dis . 2011 Jan; 2011:603052. PMID: 21234417
Lipid rafts are membrane microdomains, enriched in cholesterol and sphingolipids, into which specific subsets of proteins and lipids partition, creating cell-signalling platforms that are vital for neuronal functions. Lipid rafts...