Jiyun Zhou
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Explore the profile of Jiyun Zhou including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
275
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Recent Articles
1.
Zhou J, Luo C, Liu H, Heffel M, Straub R, Kleinman J, et al.
Cell Genom
. 2025 Feb;
5(3):100774.
PMID: 39986279
DNA methylation (DNAm) is a key epigenetic mark with essential roles in gene regulation, mammalian development, and human diseases. Single-cell technologies enable profiling DNAm at cytosines in individual cells, but...
2.
Zhou J, Weinberger D, Han S
Sci Adv
. 2025 Jan;
11(1):eadn1870.
PMID: 39742481
DNA methylation (DNAm) is essential for brain development and function and potentially mediates the effects of genetic risk variants underlying brain disorders. We present INTERACT, a transformer-based deep learning model...
3.
Su S, Liu M, Zhou J, Zhang J
Biomolecules
. 2024 Aug;
14(8).
PMID: 39199334
The interaction between microbes and drugs encompasses the sourcing of pharmaceutical compounds, microbial drug degradation, the development of , and the impact of on host drug metabolism and immune modulation....
4.
Zhou J, Luo C, Liu H, Heffel M, Straub R, Kleinman J, et al.
bioRxiv
. 2024 Feb;
PMID: 38328094
DNA methylation (DNAm), a crucial epigenetic mark, plays a key role in gene regulation, mammalian development, and various human diseases. Single-cell technologies enable the profiling of DNAm states at cytosines...
5.
Zhou J, Weinberger D, Han S
bioRxiv
. 2024 Jan;
PMID: 38293210
DNA methylation (DNAm) is essential for brain development and function and potentially mediates the effects of genetic risk variants underlying brain disorders. We present INTERACT, a transformer-based deep learning model...
6.
Zhang X, Zhou J, Yinhong Zhu , Ye X, Bo D, Tang T, et al.
Heliyon
. 2023 Jul;
9(8):e18535.
PMID: 37520974
Background: is an anaerobic Gram-negative bacterium that can lead to opportunistic infections, including Lemierre's syndrome and less common presentations of metastatic diseases. However, liver abscesses infected by in clinical settings...
7.
Zhou J, Chen Q, Braun P, Perzel Mandell K, Jaffe A, Tan H, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(34):e2206069119.
PMID: 35969790
There is growing evidence for the role of DNA methylation (DNAm) quantitative trait loci (mQTLs) in the genetics of complex traits, including psychiatric disorders. However, due to extensive linkage disequilibrium...
8.
Lan G, Zhou J, Xu R, Lu Q, Wang H
Int J Mol Sci
. 2019 Jul;
20(14).
PMID: 31336830
Transcription factor binding sites (TFBSs) play an important role in gene expression regulation. Many computational methods for TFBS prediction need sufficient labeled data. However, many transcription factors (TFs) lack labeled...
9.
Zhou J, Lu Q, Gui L, Xu R, Long Y, Wang H
Bioinformatics
. 2019 Jun;
35(24):5067-5077.
PMID: 31161194
Motivation: The prediction of transcription factor binding sites (TFBSs) is crucial for gene expression analysis. Supervised learning approaches for TFBS predictions require large amounts of labeled data. However, many TFs...
10.
Zhou J, Lu Q, Xu R, Gui L, Wang H
IEEE/ACM Trans Comput Biol Bioinform
. 2019 Jan;
17(4):1383-1393.
PMID: 30629513
Most proposed methods for TF-binding site (TFBS) predictions only use low order dependencies for predictions due to the lack of efficient methods to extract higher order dependencies. In this work,...