Jiro Kitaura
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Explore the profile of Jiro Kitaura including associated specialties, affiliations and a list of published articles.
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102
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1894
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Recent Articles
1.
Oishi K, Nakano N, Ota M, Inage E, Izawa K, Kaitani A, et al.
Allergy
. 2025 Jan;
PMID: 39868907
Background: IgE-mediated food allergy is accompanied by mucosal mast cell (MMC) hyperplasia in the intestinal mucosa. Intestinal MMC numbers correlate with the severity of food allergy symptoms. However, the mechanisms...
2.
Nagamine M, Kaitani A, Izawa K, Ando T, Yoshikawa A, Nakamura M, et al.
Front Immunol
. 2024 Dec;
15:1477072.
PMID: 39640264
Mas-related G protein-coupled receptor b2 (Mrgprb2) binding to its cationic endogenous and exogenous ligands induces mast cell degranulation and promotes inflammation in mice. However, the physiological roles of its human...
3.
Hirano T, Koyanagi A, Ago H, Yamamoto M, Kitaura J, Kasai M, et al.
Commun Biol
. 2024 Aug;
7(1):1042.
PMID: 39179708
Immunoglobulin E (IgE) plays pivotal roles in allergic diseases through interaction with a high-affinity receptor (FcεRI). We established that Fab fragments of anti-IgE antibodies (HMK-12 Fab) rapidly dissociate preformed IgE-FcεRI...
4.
Muela-Zarzuela I, Suarez-Rivero J, Gallardo-Orihuela A, Wang C, Izawa K, de Gregorio-Procopio M, et al.
Inflamm Res
. 2024 Jun;
73(8):1253-1266.
PMID: 38907167
Background: Senescence is a cellular aging-related process triggered by different stresses and characterized by the secretion of various inflammatory factors referred to as senescence-associated secretory phenotype (SASP), some of which...
5.
Ando T, Takazawa I, Spencer Z, Ito R, Tomimori Y, Mikulski Z, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891118
Crohn's disease is a chronic, debilitating, inflammatory bowel disease. Here, we report a critical role of phospholipase C-β3 (PLC-β3) in intestinal homeostasis. In PLC-β3-deficient mice, exposure to oral dextran sodium...
6.
Ide T, Izawa K, Diono W, Kamei A, Ando T, Kaitani A, et al.
Sci Rep
. 2024 Apr;
14(1):8398.
PMID: 38600251
Allergic rhinitis (AR) is caused by type I hypersensitivity reaction in the nasal tissues. The interaction between CD300f and its ligand ceramide suppresses immunoglobulin E (IgE)-mediated mast cell activation. However,...
7.
Yamamoto R, Ando T, Kitaura J, Narita M, Miura K, Takasato Y, et al.
J Allergy Clin Immunol Pract
. 2023 Nov;
12(3):786-788.e1.
PMID: 37984796
No abstract available.
8.
Kimura M, Ando T, Kume Y, Fukase S, Matsuzawa M, Kashiwagi K, et al.
JCI Insight
. 2023 Oct;
8(21.
PMID: 37819721
The penetration of allergens through the epithelial layer is the initial step in the development of allergic conjunctivitis. Although pollinosis patients manifest symptoms within minutes after pollen exposure, the mechanisms...
9.
Yamamoto R, Izawa K, Ando T, Kaitani A, Tanabe A, Yamada H, et al.
Front Immunol
. 2023 Sep;
14:1238297.
PMID: 37711608
Background: Recently, we have developed a method to identify IgE cross-reactive allergens. However, the mechanism by which IgE cross-reactive allergens cause food allergy is not yet fully understood how. In...
10.
Zhang Z, Shibata T, Fujimura A, Kitaura J, Miyake K, Ohto U, et al.
Nature
. 2023 Sep;
622(7981):188-194.
PMID: 37704723
Inflammasome sensors detect pathogen- and danger-associated molecular patterns and promote inflammation and pyroptosis. NLRP1 was the first inflammasome sensor to be described, and its hyperactivation is linked to autoinflammatory disease...