Jin Billy Li
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Explore the profile of Jin Billy Li including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Breen M, Dobbyn A, Li Q, Roussos P, Hoffman G, Stahl E, et al.
Nat Neurosci
. 2019 Aug;
22(9):1402-1412.
PMID: 31455887
RNA editing critically regulates neurodevelopment and normal neuronal function. The global landscape of RNA editing was surveyed across 364 schizophrenia cases and 383 control postmortem brain samples from the CommonMind...
22.
Bhate A, Sun T, Li J
Mol Cell
. 2019 Mar;
73(5):866-868.
PMID: 30849393
Three recent studies by Ishizuka et al. (2019), Liu et al. (2019), and Gannon et al. (2018) show that deleting RNA editing enzyme ADAR1 could induce higher cell lethality and...
23.
Merkle T, Merz S, Reautschnig P, Blaha A, Li Q, Vogel P, et al.
Nat Biotechnol
. 2019 Jan;
37(2):133-138.
PMID: 30692694
Site-directed RNA editing might provide a safer or more effective alternative to genome editing in certain clinical scenarios. Until now, RNA editing has relied on overexpression of exogenous RNA editing...
24.
Sapiro A, Shmueli A, Henry G, Li Q, Shalit T, Yaron O, et al.
Proc Natl Acad Sci U S A
. 2019 Jan;
116(6):2318-2327.
PMID: 30659150
Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by ADAR enzymes, is a ubiquitous mechanism that generates transcriptomic diversity. This process is particularly important for proper neuronal function; however, little is known about...
25.
Maeder C, Kim J, Liang X, Kaganovsky K, Shen A, Li Q, et al.
Cell
. 2018 Aug;
174(6):1436-1449.e20.
PMID: 30146163
Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular mechanisms for coordinated synthesis of these proteins are not understood. Using forward genetic screens, we identified the conserved...
26.
Yesselman J, Tian S, Liu X, Shi L, Li J, Das R
Nucleic Acids Res
. 2018 Jul;
46(D1):D375-D379.
PMID: 30053264
Chemical mapping is a broadly utilized technique for probing the structure and function of RNAs. The volume of chemical mapping data continues to grow as more researchers routinely employ this...
27.
Vogel P, Moschref M, Li Q, Merkle T, Selvasaravanan K, Li J, et al.
Nat Methods
. 2018 Jul;
15(7):535-538.
PMID: 29967493
Molecular tools that target RNA at specific sites allow recoding of RNA information and processing. SNAP-tagged deaminases guided by a chemically stabilized guide RNA can edit targeted adenosine to inosine...
28.
Yablonovitch A, Deng P, Jacobson D, Li J
PLoS Genet
. 2017 Nov;
13(11):e1007064.
PMID: 29182635
Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to RNA to protein. RNA editing can generate a multitude of transcript isoforms and...
29.
Yablonovitch A, Fu J, Li K, Mahato S, Kang L, Rashkovetsky E, et al.
Nat Commun
. 2017 Nov;
8(1):1570.
PMID: 29146998
Determining the mechanisms by which a species adapts to its environment is a key endeavor in the study of evolution. In particular, relatively little is known about how transcriptional processes...
30.
Walkley C, Li J
Genome Biol
. 2017 Nov;
18(1):205.
PMID: 29084589
One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes. The functional requirement and...