Jin-Ichi Ito
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Explore the profile of Jin-Ichi Ito including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
175
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Recent Articles
1.
Abdullah M, Takase H, Nunome M, Enomoto H, Ito J, Gong J, et al.
J Alzheimers Dis
. 2016 Jul;
53(4):1433-41.
PMID: 27392863
Exosomes are small extracellular vesicles secreted by variety of cell types such as neurons, astrocytes, and oligodendrocytes. It is suggested that exosomes play essential role in the maintenance of the...
2.
Ito J, Nagayasu Y, Ogawa T, Okihara H, Michikawa M
Brain Res
. 2015 Apr;
1615:1-11.
PMID: 25881893
Oxidative stress induced by the treatment with 100 µM hydrogen peroxide (H2O2) for 10 min enhances release of cytosolic proteins along with fibroblast growth factor 1 (FGF-1) from rat astrocytes...
3.
Ito J, Lu R, Nagayasu Y, Yokoyama S
Biochim Biophys Acta
. 2014 May;
1841(9):1234-40.
PMID: 24814947
We previously identified cytosolic lipid-protein particles (CLPP) having size and density of HDL in rat astrocytes, to which apoA-I induces translocation of cholesterol, caveolin-1 and protein kinase Cα (PKCα) following...
4.
Ito J, Nagayasu Y, Miura Y, Yokoyama S, Michikawa M
Brain Res
. 2014 May;
1570:1-12.
PMID: 24814386
Apolipoprotein E (apoE) in the brain is predominantly synthesized in and secreted from astrocytes to generate apoE-containing high-density lipoprotein-like particles (apoE/HDL). However, the mechanism underlying generation of apoE/HDL has not...
5.
Nagayasu Y, Morita S, Hayashi H, Miura Y, Yokoyama K, Michikawa M, et al.
Brain Res
. 2014 Apr;
1563:31-40.
PMID: 24690199
We found in a previous study that both mRNA expression and release of fibroblast growth factor 1 (FGF-1) are greater in rat astrocytes that are long term-cultured for one month...
6.
Okihara H, Ito J, Kokai S, Ishida T, Hiranuma M, Kato C, et al.
J Neurosci Res
. 2014 Apr;
92(8):1010-7.
PMID: 24687840
It is suggested that masticatory dysfunction affects the central nervous system; however, the underlying mechanism remains unknown. Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are known to play important...
7.
Kheirollah A, Nagayasu Y, Ueda H, Yokoyama S, Michikawa M, Ito J
J Neurosci Res
. 2014 Jan;
92(4):455-63.
PMID: 24446142
Activation of cdc42 reportedly enhances apoA-I-mediated cholesterol release through ATP-binding cassette transporter A1 (ABCA1). We examined the involvement of cdc42 and Rho kinase in intracellular cholesterol transport for release of...
8.
Ito J, Nagayasu Y, Hoshikawa M, Kato K, Miura Y, Asai K, et al.
Brain Res
. 2013 Jun;
1522:12-21.
PMID: 23727614
We previously observed that the production and release of fibroblast growth factor (FGF-1) are increased in rat astrocytes during in vitro long-term culture, that FGF-1 enhances the generation of apoE-containing...
9.
Ito J, Nagayasu Y, Kheirollah A, Abe-Dohmae S, Yokoyama S
Biochim Biophys Acta
. 2011 Sep;
1811(12):1062-9.
PMID: 21907307
In the previous paper, we reported that apolipoprotein (apo) A-I enhances generation of HDL-like lipoproteins in rat astrocytes to be accompanied with both increase in tyrosine phosphorylation of phospholipase Cγ...
10.
Mori-Kawabe M, Tsushima H, Fujimoto S, Tada T, Ito J
J Atheroscler Thromb
. 2009 Sep;
16(6):722-32.
PMID: 19755789
Aim: Atherosclerosis is a cardiovascular disease; however, there is little information on signal transduction for vascular function in the early stage of atherosclerosis. In this work, we investigated the role...