Jimmy D Ballard
Overview
Explore the profile of Jimmy D Ballard including associated specialties, affiliations and a list of published articles.
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Articles
79
Citations
1658
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Recent Articles
11.
Amadou Amani S, Lang G, Ballard J, Lang M
Infect Immun
. 2021 Jun;
89(10):e0027421.
PMID: 34097471
The pathology associated with Clostridioides difficile disease is caused in large part by TcdB, an intracellular bacterial toxin that inactivates small GTPases. Despite C. difficile causing enteric disease, antitoxin IgG...
12.
Ahmed U, Shadid T, Larabee J, Ballard J
mBio
. 2021 Jan;
11(6).
PMID: 33443122
The accessory gene regulator 1 () locus consists of two genes, and , that presumably constitute an autoinducing peptide (AIP) system. Typically, AIP systems function through the AgrB-mediated processing of...
13.
Recommendations for future university pandemic responses: What the first COVID-19 shutdown taught us
Coyne C, Ballard J, Blader I
PLoS Biol
. 2020 Aug;
18(8):e3000889.
PMID: 32853196
The SARS-CoV-2 epidemic challenged universities and other academic institutions to rapidly adapt to urgent and life-threatening situations. It forced most institutions to shut down nearly every aspect of their research...
14.
Shah H, Smith K, Scott 2nd E, Larabee J, James J, Ballard J, et al.
JCI Insight
. 2020 Jul;
5(16.
PMID: 32663199
Clostridioides difficile is a leading cause of nosocomial infection responsible for significant morbidity and mortality with limited options for therapy. Secreted C. difficile toxin B (TcdB) is a major contributor...
15.
Dumas E, Demiraslan H, Ingram R, Sparks R, Muns E, Zamora A, et al.
PLoS One
. 2020 Apr;
15(4):e0230782.
PMID: 32294093
Understanding immune responses to native antigens in response to natural infections can lead to improved approaches to vaccination. This study sought to characterize the humoral immune response to anthrax toxin...
16.
17.
Amadou Amani S, Shadid T, Ballard J, Lang M
Infect Immun
. 2019 Dec;
88(3).
PMID: 31871095
The intracellularly active bacterial toxin TcdB is a major virulence factor that contributes to inflammation and tissue damage during disease. Immunization with an inactive TcdB fragment prevents infection (CDI)-associated pathology....
18.
Bland S, Larabee J, Shadid T, Lang M, Ballard J
Infect Immun
. 2019 May;
87(8).
PMID: 31138612
toxin B (TcdB) is an intracellular toxin responsible for many of the pathologies of infection. The two variant forms of TcdB (TcdB1 and TcdB2) share 92% sequence identity but have...
19.
Shah H, Smith K, Wren J, Webb C, Ballard J, Bourn R, et al.
Front Immunol
. 2019 Jan;
9:3064.
PMID: 30697210
Memory B cells that are generated during an infection or following vaccination act as sentinels to guard against future infections. Upon repeat antigen exposure memory B cells differentiate into new...
20.
Unique, Intersecting, and Overlapping Roles of C/EBP β and CREB in Cells of the Innate Immune System
Larabee J, Hauck G, Ballard J
Sci Rep
. 2018 Nov;
8(1):16931.
PMID: 30446701
CREB and C/EBP β signaling pathways are modulated during inflammation and also targeted by Bacillus anthracis edema toxin (ET), but how these factors individually and jointly contribute to changes in...