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Jim Petrik

Explore the profile of Jim Petrik including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 544
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Recent Articles
11.
Son J, Chow R, Kim H, Lieu T, Xiao M, Kim S, et al.
Reprod Biol Endocrinol . 2023 Aug; 21(1):75. PMID: 37612696
Objective: To systematically identify and narratively synthesize the evidence surrounding liposomal delivery of gene therapy and the outcome for ovarian cancer. Methods: An electronic database search of the Embase, MEDLINE...
12.
Pereira M, Matuszewska K, Glogova A, Petrik J
Cancers (Basel) . 2022 Jul; 14(14). PMID: 35884561
Tumor cells have the ability to co-opt multiple metabolic pathways, enhance glucose uptake and utilize aerobic glycolysis to promote tumorigenesis, which are characteristics constituting an emerging hallmark of cancer. Mutated...
13.
Pereira M, Matuszewska K, Jamieson C, Petrik J
Front Endocrinol (Lausanne) . 2021 Dec; 12:772349. PMID: 34867818
Epithelial ovarian cancer is predominantly diagnosed at advanced stages which creates significant therapeutic challenges. As a result, the 5-year survival rate is low. Within ovarian cancer, significant tumor heterogeneity exists,...
14.
Matuszewska K, Ten Kortenaar S, Pereira M, Santry L, Petrik D, Lo K, et al.
Gynecol Oncol . 2021 Nov; 164(1):154-169. PMID: 34799137
Objectives: Tumor vasculature is structurally abnormal, with anatomical deformities, reduced pericyte coverage and low tissue perfusion. As a result of this vascular dysfunction, tumors are often hypoxic, which is associated...
15.
Ram A, Matuszewska K, Petrik J, Singh A, Oblak M
Front Vet Sci . 2021 Nov; 8:758295. PMID: 34746290
To develop a digital algorithm for quantitative assessment of surface methylene blue staining in whole lymph nodes and validate a semi-quantitative visual scoring method for patient-side use. Lymph nodes from...
16.
Matuszewska K, Pereira M, Petrik D, Lawler J, Petrik J
Cancers (Basel) . 2021 Sep; 13(17). PMID: 34503254
A basic requirement of tumorigenesis is the development of a vascular network to support the metabolic requirements of tumor growth and metastasis. Tumor vascular formation is regulated by a balance...
17.
Morandi V, Petrik J, Lawler J
Front Cell Dev Biol . 2021 Apr; 9:664696. PMID: 33869231
The thrombospondins (TSPs) are a family of multimeric extracellular matrix proteins that dynamically regulate cellular behavior and response to stimuli. In so doing, the TSPs directly and indirectly affect biological...
18.
Pal P, Hales K, Petrik J, Hales D
J Ovarian Res . 2019 May; 12(1):49. PMID: 31128594
Background: We have previously shown that a whole flaxseed supplemented diet decreased the onset and severity of ovarian cancer in the laying hen, the only known animal model of spontaneous...
19.
Matuszewska K, Santry L, van Vloten J, AuYeung A, Major P, Lawler J, et al.
Clin Cancer Res . 2018 Sep; 25(5):1624-1638. PMID: 30206160
Purpose: Intravenous delivery of oncolytic viruses often leads to tumor vascular shutdown, resulting in decreased tumor perfusion and elevated tumor hypoxia. We hypothesized that using 3TSR to normalize tumor vasculature...
20.
Kellenberger L, Petrik J
Gynecol Oncol . 2018 Feb; 149(2):361-370. PMID: 29458977
Introduction: Epithelial ovarian cancer (EOC) is notoriously difficult to diagnose in its earlier and more treatable stages, making it one of the deadliest cancers in women. Comorbid diabetes is associated...