Jihee Lee Kang
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Explore the profile of Jihee Lee Kang including associated specialties, affiliations and a list of published articles.
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79
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1391
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Recent Articles
11.
Kim H, Yang K, Kim K, Lee Y, Lee S, Ahn S, et al.
Cell Mol Immunol
. 2022 Oct;
19(12):1373-1391.
PMID: 36241874
The interplay between apoptotic cancer cells and the tumor microenvironment modulates cancer progression and metastasis. Cancer-associated fibroblasts (CAFs) play a crucial role in promoting these events through paracrine communication. Here,...
12.
Park J, Leem Y, Park J, Kim D, Kang J, Kim H
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457238
Neuroinflammation is crucial in the progression of neurodegenerative diseases. Thus, controlling neuroinflammation has been proposed as an important therapeutic strategy for neurodegenerative disease. In the present study, we examined the...
13.
Lee Y, Kim K, Kim M, Ahn Y, Kang J
Biomolecules
. 2022 Mar;
12(3).
PMID: 35327639
Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory process by inducing the development of M2 macrophages. We investigated whether modulating STAT6 activity in macrophages using AS1517499, the...
14.
Kim B, Lee Y, Choi Y, Park E, Kang J
Biomedicines
. 2021 Nov;
9(11).
PMID: 34829903
Acute lung injury (ALI) is characterized by alveolar damage, lung edema, and exacerbated inflammatory response. Growth arrest-specific protein 6 (Gas6) mediates many different functions, including cell survival, proliferation, inflammatory signaling,...
15.
Kim H, Moon C, Kang J, Park E
Korean J Physiol Pharmacol
. 2021 Oct;
25(6):575-583.
PMID: 34697268
Composition of the gut microbiota changes with aging and plays an important role in age-associated disease such as metabolic syndrome, cancer, and neurodegeneration. The gut microbiota composition oscillates through the...
16.
Lee S, Hong J, Kim J, Yoon J, Chun S, Hong S, et al.
Cancer Lett
. 2021 Mar;
508:92-103.
PMID: 33775710
Fibroblasts in the tumor microenvironment, known as cancer-associated fibroblasts (CAFs), promote the migration, invasion, and metastasis of cancer cells when they are activated through diverse processes, including post-transcriptional regulation by...
17.
Lee Y, Kim B, Ahn Y, Choi J, Choi Y, Kang J
Cells
. 2021 Mar;
10(3).
PMID: 33652833
The signal transducer and activator of transcription 6 (STAT6) transcription factor promotes activation of the peroxisome proliferator-activated receptor gamma (PPARγ) pathway in macrophages. Little is known about the effect of...
18.
Kim T, Yang K, Kim M, Kim H, Kang J
Cell Death Dis
. 2021 Jan;
12(1):19.
PMID: 33414479
Apoptosis inhibitor of macrophage (AIM) modulates the signaling in inflammatory responses, including infection, cancer, or other immune diseases. Recent studies suggest that like interleukin-10 (IL-10), AIM is involved in alternatively...
19.
Shin J, Kim H, Kang J, Park E
Neurobiol Aging
. 2020 Sep;
96:33-42.
PMID: 32920472
The total iron level in the brain increases with age, and excess iron is associated with neurodegenerative diseases; however, the mechanism of brain iron deposition is unknown. In peripheral cells,...
20.
Leem Y, Park J, Park J, Kim D, Kang J, Kim H
Biomed Pharmacother
. 2020 Aug;
130:110576.
PMID: 32768884
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor impairments. Most PD drugs act by improving motor impairments, whereas very few drugs that efficiently recover PD-related neuropathological features, particularly...