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Jianzhuo Li

Explore the profile of Jianzhuo Li including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 219
Followers 0
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Recent Articles
1.
Lin Y, Wang J, Wang K, Bai S, Thennavan A, Wei R, et al.
Nature . 2024 Nov; 636(8043):663-670. PMID: 39567687
Aneuploid epithelial cells are common in breast cancer; however, their presence in normal breast tissues is not well understood. To address this question, we applied single-cell DNA sequencing to profile...
2.
Wang K, Yan Y, Elgamal H, Li J, Tang C, Bai S, et al.
bioRxiv . 2024 Sep; PMID: 39314325
Understanding the impact of genetic alterations on epigenomic phenotypes during breast cancer progression is challenging with unimodal measurements. Here, we report wellDA-seq, the first high-genomic resolution, high-throughput method that can...
3.
Gupta P, Dang M, Oberai S, Migliozzi S, Trivedi R, Kumar G, et al.
Neuro Oncol . 2024 Aug; 26(12):2239-2255. PMID: 39126294
Background: Human gliomas are classified using isocitrate dehydrogenase (IDH) status as a prognosticator; however, the influence of genetic differences and treatment effects on ensuing immunity remains unclear. Methods: In this...
4.
Wang K, Kumar T, Wang J, Minussi D, Sei E, Li J, et al.
Cell . 2023 Aug; 186(18):3968-3982.e15. PMID: 37586362
Ductal carcinoma in situ (DCIS) is a common precursor of invasive breast cancer. Our understanding of its genomic progression to recurrent disease remains poor, partly due to challenges associated with...
5.
Kumar T, Nee K, Wei R, He S, Nguyen Q, Bai S, et al.
Nature . 2023 Jun; 620(7972):181-191. PMID: 37380767
The adult human breast is comprised of an intricate network of epithelial ducts and lobules that are embedded in connective and adipose tissue. Although most previous studies have focused on...
6.
Kumar T, Nee K, Wei R, He S, Nguyen Q, Bai S, et al.
bioRxiv . 2023 May; PMID: 37163043
The adult human breast comprises an intricate network of epithelial ducts and lobules that are embedded in connective and adipose tissue. While previous studies have mainly focused on the breast...
7.
Lu L, Wang J, Henderson Y, Bai S, Yang J, Hu M, et al.
J Clin Invest . 2023 Apr; 133(11). PMID: 37053016
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by...
8.
Jiao K, Liao M, Liu G, Bi Y, Zhao X, Chen Q, et al.
AIDS Res Ther . 2022 Nov; 19(1):55. PMID: 36424621
Background: Consistent and complete adherence is considered an essential requirement for patients on antiretroviral therapy (ART). This study aimed to evaluate the impact of ART duration on ART adherence, identify...
9.
Li J, Fu X, Cao S, Li J, Xing S, Li D, et al.
J Biol Chem . 2018 Jun; 293(33):12719-12729. PMID: 29934310
The androgen receptor (AR) is a ligand-activated nuclear receptor that plays a critical role in normal prostate physiology, as well as in the development and progression of prostate cancer. In...
10.
Liu X, Ledet E, Li D, Dotiwala A, Steinberger A, Feibus A, et al.
J Urol . 2016 Jul; 196(6):1758-1763. PMID: 27449259
Purpose: Most prostate cancer mortality can be attributed to metastatic castration resistant prostate cancer, an advanced stage that remains incurable despite recent advances. The AR (androgen receptor) signaling axis remains...