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Jianzhao Xu

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Articles 62
Citations 1079
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Recent Articles
1.
Karere G, Hsu F, Hepple R, Coen P, Cummings S, Newman A, et al.
bioRxiv . 2025 Jan; PMID: 39829832
Background: Peak oxygen consumption during exercise (VO peak), is a direct measure of cardiorespiratory fitness (CF), a key indicator of physical function and overall health. However, the molecular changes that...
2.
Kavousi M, Bos M, Barnes H, Lino Cardenas C, Wong D, Lu H, et al.
Nat Genet . 2023 Sep; 55(10):1651-1664. PMID: 37770635
Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may point to new therapeutic avenues for prevention....
3.
Chevli P, Freedman B, Hsu F, Xu J, Rudock M, Ma L, et al.
Cardiovasc Diabetol . 2021 Dec; 20(1):231. PMID: 34876126
Background: Incidence rates of cardiovascular disease (CVD) are increasing, partly driven by the diabetes epidemic. Novel prediction tools and modifiable treatment targets are needed to enhance risk assessment and management....
4.
Palmer N, Lu L, Register T, Lenchik L, Carr J, Hicks P, et al.
PLoS One . 2021 May; 16(5):e0251423. PMID: 34014961
Relative to European Americans, African Americans have lower 25-hydroxyvitamin D (25OHD) and vitamin D binding protein (VDBP) concentrations, higher 1,25-dihydroxyvitamin D (1,25(OH)2D3) concentrations and bone mineral density (BMD), and paradoxically...
5.
Li G, Wang G, Hsu F, Xu J, Pei X, Zhao B, et al.
Am J Trop Med Hyg . 2020 Mar; 102(5):988-994. PMID: 32124716
Chronic hepatitis B virus (HBV) infection is a major public health problem in China. We evaluated the impact of psychosocial factors (stigma, disclosure, depression, and anxiety) on health-related quality of...
6.
Brown L, Xu J, Freedman B, Hsu F, Bowden D, Koch K
Dig Dis Sci . 2019 Dec; 65(8):2321-2330. PMID: 31820181
Background: Although gastroparesis is seen in patients with type 2 diabetes mellitus (T2DM), the prevalence of symptoms suggestive of gastroparesis in patients with T2DM is unknown, particularly among African Americans....
7.
Saghafi B, Garg P, Wagner B, Smith S, Xu J, Madhuranthakam A, et al.
The effect of Type 2 Diabetes (T2D) on brain health is poorly understood. This study aims to quantify the association between T2D and perfusion in the brain. T2D is a...
8.
Liu M, Frej C, Langefeld C, Divers J, Bowden D, Carr J, et al.
J Lipid Res . 2019 May; 60(8):1425-1431. PMID: 31133557
apoM is a minor HDL apolipoprotein and carrier for sphingosine-1-phosphate (S1P). HDL apoM and S1P concentrations are inversely associated with atherosclerosis progression in rodents. We evaluated associations between plasma concentrations...
9.
Guan M, Keaton J, Dimitrov L, Hicks P, Xu J, Palmer N, et al.
Hum Genomics . 2019 May; 13(1):21. PMID: 31092297
Background: End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and...
10.
Hughes T, Sink K, Williamson J, Hugenschmidt C, Wagner B, Whitlow C, et al.
J Diabetes Complications . 2018 Jul; 32(10):916-921. PMID: 30042057
Background: Relationships between cognitive function and brain structure remain poorly defined in African Americans with type 2 diabetes. Methods: Cognitive testing and cerebral magnetic resonance imaging in African Americans from...