Jiang I Wu
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Explore the profile of Jiang I Wu including associated specialties, affiliations and a list of published articles.
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18
Citations
1503
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Recent Articles
1.
Deng H, Guo X, Feng N, Luo Y, Liu B, Liu S, et al.
Front Oncol
. 2022 Dec;
12:1057147.
PMID: 36531063
Previously we uncovered the epigenetic regulation of medulloblastoma that low levels of H3K27me3 are required for Shh target gene expression and medulloblastoma growth. Since Jmjd3, an H3K27me3 demethylase, is responsible...
2.
Zhang Z, Cao M, Chang C, Wang C, Shi X, Zhan X, et al.
Mol Cell Biol
. 2015 Oct;
36(1):70-83.
PMID: 26459759
Synapse development requires normal neuronal activities and the precise expression of synapse-related genes. Dysregulation of synaptic genes results in neurological diseases such as autism spectrum disorders (ASD). Mutations in genes...
3.
Petrik D, Latchney S, Masiulis I, Yun S, Zhang Z, Wu J, et al.
Stem Cells
. 2015 Sep;
33(12):3655-65.
PMID: 26418130
Insights from embryonic development suggest chromatin remodeling is important in adult neural stem cells (aNSCs) maintenance and self-renewal, but this concept has not been fully explored in the adult brain....
4.
Zhan X, Cao M, Yoo A, Zhang Z, Chen L, Crabtree G, et al.
Genesis
. 2015 Jun;
53(7):440-8.
PMID: 26077106
Molecular and functional studies of genes in neurons in mouse models require neuron-specific Cre lines. The current available neuronal Cre transgenic or knock-in lines either result in expression in a...
5.
Cao M, Wu J
Neurosci Lett
. 2015 May;
597:71-6.
PMID: 25929186
Mammalian SWI/SNF-like BAF chromatin remodeling complexes are essential for many aspects of neural development. Mutations in the genes encoding the core subunit Brg1/SmarcA4 or other complex components cause neurodevelopmental diseases...
6.
Vogel-Ciernia A, Matheos D, Barrett R, Kramar E, Azzawi S, Chen Y, et al.
Nat Neurosci
. 2013 Mar;
16(5):552-61.
PMID: 23525042
Recent exome sequencing studies have implicated polymorphic Brg1-associated factor (BAF) complexes (mammalian SWI/SNF chromatin remodeling complexes) in several human intellectual disabilities and cognitive disorders. However, it is currently unknown how...
7.
Wu J
Acta Biochim Biophys Sin (Shanghai)
. 2011 Dec;
44(1):54-69.
PMID: 22194014
Mammalian SWI/SNF like Brg1/Brm associated factors (BAF) chromatin-remodeling complexes are able to use energy derived from adenosine triphosphate (ATP) hydrolysis to change chromatin structures and regulate nuclear processes such as...
8.
Zhan X, Shi X, Zhang Z, Chen Y, Wu J
Proc Natl Acad Sci U S A
. 2011 Jul;
108(31):12758-63.
PMID: 21768360
Sonic hedgehog (Shh) signaling plays diverse roles during animal development and adult tissue homeostasis through differential regulation of Gli family transcription factors. Dysregulated Shh signaling activities have been linked to...
9.
Artzt K, Wu J
Adv Exp Med Biol
. 2010 Dec;
693:1-24.
PMID: 21189682
The STAR family has an extremely diverse role during development and in RNA metabolism. We have concentrated on QKI as an example of this pleiotropic activity and also presented some...
10.
Wu J, Lessard J, Crabtree G
Cell
. 2009 Jan;
136(2):200-6.
PMID: 19167321
Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical...