Jian Min Ren
Overview
Explore the profile of Jian Min Ren including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
9
Citations
1462
Followers
0
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Recent Articles
1.
Rodrigues-Amorim D, Bozzelli P, Kim T, Liu L, Gibson O, Yang C, et al.
Nat Commun
. 2024 Aug;
15(1):6744.
PMID: 39112447
Demyelination is a common pathological feature in a wide range of diseases, characterized by the loss of myelin sheath and myelin-supporting oligodendrocytes. These losses lead to impaired axonal function, increased...
2.
Searle B, Chien A, Koller A, Hawke D, Herren A, Kim J, et al.
Mol Cell Proteomics
. 2023 Sep;
22(10):100639.
PMID: 37657519
Recent advances in methodology have made phosphopeptide analysis a tractable problem for many proteomics researchers. There are now a wide variety of robust and accessible enrichment strategies to generate phosphoproteomes...
3.
Nelson A, Zhu Y, Min Ren J, Stokes M
Methods Mol Biol
. 2021 Aug;
2365:203-216.
PMID: 34432246
Ubiquitination is a post-translational modification that affects protein degradation as well as a variety of cellular processes. Methods that globally profile ubiquitination are powerful tools to better understand these processes....
4.
Stokes M, Farnsworth C, Gu H, Jia X, Worsfold C, Yang V, et al.
Proteomes
. 2017 Mar;
3(3):160-183.
PMID: 28248267
Gaining insight into normal cellular signaling and disease biology is a critical goal of proteomic analyses. The ability to perform these studies successfully to extract the maximum value and discovery...
5.
Gu H, Min Ren J, Jia X, Levy T, Rikova K, Yang V, et al.
Mol Cell Proteomics
. 2015 Dec;
15(2):692-702.
PMID: 26635363
A robust method was developed and optimized for enrichment and quantitative analysis of posttranslational modifications (PTMs) in serum/plasma samples by combining immunoaffinity purification and LC-MS/MS without depletion of abundant proteins....
6.
Moritz A, Li Y, Guo A, Villen J, Wang Y, MacNeill J, et al.
Sci Signal
. 2010 Aug;
3(136):ra64.
PMID: 20736484
Receptor tyrosine kinases (RTKs) activate pathways mediated by serine-threonine kinases, such as the PI3K (phosphatidylinositol 3-kinase)-Akt pathway, the Ras-MAPK (mitogen-activated protein kinase)-RSK (ribosomal S6 kinase) pathway, and the mTOR (mammalian...
7.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, et al.
Cell
. 2007 Dec;
131(6):1190-203.
PMID: 18083107
Despite the success of tyrosine kinase-based cancer therapeutics, for most solid tumors the tyrosine kinases that drive disease remain unknown, limiting our ability to identify drug targets and predict response....
8.
Stokes M, Rush J, MacNeill J, Min Ren J, Sprott K, Nardone J, et al.
Proc Natl Acad Sci U S A
. 2007 Dec;
104(50):19855-60.
PMID: 18077418
To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia telangiectasia-mutated (ATM)...
9.
Min Ren J, Rejtar T, Li L, Karger B
J Proteome Res
. 2007 Jul;
6(8):3162-73.
PMID: 17625816
While glycoproteins are abundant in nature, and changes in glycosylation occur in cancer and other diseases, glycoprotein characterization remains a challenge due to the structural complexity of the biopolymers. This...