Jheralyn Martin
Overview
Explore the profile of Jheralyn Martin including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
332
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0
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Recent Articles
1.
Holmes B, Artinian N, Anderson L, Martin J, Masri J, Cloninger C, et al.
Cell Signal
. 2011 Oct;
24(1):309-15.
PMID: 21964062
The A/U-rich RNA-binding protein tristetraprolin (TTP) is an mRNA destabilizing factor which plays a role in the regulated turnover of many transcripts encoding proteins involved in immune function and cell...
2.
Martin J, Masri J, Cloninger C, Holmes B, Artinian N, Funk A, et al.
J Biol Chem
. 2011 Apr;
286(18):16402-13.
PMID: 21454539
The relative activity of the AKT kinase has been demonstrated to be a major determinant of sensitivity of tumor cells to mammalian target of rapamycin (mTOR) complex 1 inhibitors. Our...
3.
Vartanian R, Masri J, Martin J, Cloninger C, Holmes B, Artinian N, et al.
Mol Cancer Res
. 2010 Dec;
9(1):115-30.
PMID: 21135252
One mechanism by which AKT kinase-dependent hypersensitivity to mammalian target of rapamycin (mTOR) inhibitors is controlled is by the differential expression of cyclin D1 and c-MYC. Regulation of posttranscriptional processes...
4.
Jo O, Martin J, Bernath A, Masri J, Lichtenstein A, Gera J
J Biol Chem
. 2008 Jun;
283(34):23274-87.
PMID: 18562319
The translation of the cyclin D1 and c-myc mRNAs occurs via internal ribosome entry site (IRES)-mediated initiation under conditions of reduced eIF-4F complex formation and Akt activity. Here we identify...
5.
Martin J, Masri J, Bernath A, Nishimura R, Gera J
Biochem Biophys Res Commun
. 2008 May;
372(4):578-83.
PMID: 18505677
mTORC2 is a multiprotein kinase composed of mTOR, mLST8, PRR5, mSIN1 and Rictor. The complex is insensitive to rapamycin and has demonstrated functions controlling cell growth, motility, invasion and cytoskeletal...
6.
Masri J, Bernath A, Martin J, Jo O, Vartanian R, Funk A, et al.
Cancer Res
. 2007 Dec;
67(24):11712-20.
PMID: 18089801
mTORC2 is a multimeric kinase composed of the mammalian target of rapamycin kinase (mTOR), mLST8, mSin1, and rictor. The complex is insensitive to acute rapamycin exposure and has shown functions...
7.
Sharma A, Masri J, Jo O, Bernath A, Martin J, Funk A, et al.
J Biol Chem
. 2007 Feb;
282(13):9505-9516.
PMID: 17284439
GATA-4 is a key member of the GATA family of transcription factors involved in cardiac development and growth as well as in cardiac hypertrophy and heart failure. Our previous studies...