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Jett Crowdis

Explore the profile of Jett Crowdis including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 330
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Recent Articles
1.
Gillani R, Collins R, Crowdis J, Garza A, Jones J, Walker M, et al.
Science . 2025 Jan; 387(6729):eadq0071. PMID: 39745975
Pediatric solid tumors are a leading cause of childhood disease mortality. In this work, we examined germline structural variants (SVs) as risk factors for pediatric extracranial solid tumors using germline...
2.
Asantewaa G, Tuttle E, Ward N, Kang Y, Kim Y, Kavanagh M, et al.
Nat Commun . 2024 Jul; 15(1):6152. PMID: 39034312
Cells rely on antioxidants to survive. The most abundant antioxidant is glutathione (GSH). The synthesis of GSH is non-redundantly controlled by the glutamate-cysteine ligase catalytic subunit (GCLC). GSH imbalance is...
3.
Conway J, Gillani R, Crowdis J, Reardon B, Park J, Han S, et al.
J Clin Invest . 2024 May; 134(13). PMID: 38758740
The diversity of structural variants (SVs) in melanoma and how they impact oncogenesis are incompletely known. We performed harmonized analysis of SVs across melanoma histologic and genomic subtypes, and we...
4.
Gillani R, Collins R, Crowdis J, Garza A, Jones J, Walker M, et al.
bioRxiv . 2024 May; PMID: 38746320
Pediatric solid tumors are rare malignancies that represent a leading cause of death by disease among children in developed countries. The early age-of-onset of these tumors suggests that germline genetic...
5.
Conway J, Tewari A, Camp S, Han S, Crowdis J, He M, et al.
bioRxiv . 2023 Mar; PMID: 36993558
Statement Of Significance: Tumors from patients who self-reported as Black demonstrate linear and monoclonal evolutionary trajectories yet experience higher rates of biochemical recurrence. In addition, analysis of clonal and subclonal...
6.
Doe-Tetteh S, Camp S, Reales D, Crowdis J, Noronha A, Wolff B, et al.
Clin Cancer Res . 2023 Mar; 29(13):2445-2455. PMID: 36862133
Purpose: To overcome barriers to genomic testing for patients with rare cancers, we initiated a program to offer free clinical tumor genomic testing worldwide to patients with select rare cancer...
7.
Asantewaa G, Tuttle E, Ward N, Kang Y, Kim Y, Kavanagh M, et al.
bioRxiv . 2023 Feb; PMID: 36798186
Cells rely on antioxidants to survive. The most abundant antioxidant is glutathione (GSH). The synthesis of GSH is non-redundantly controlled by the glutamate-cysteine ligase catalytic subunit (GCLC). GSH imbalance is...
8.
Crowdis J, Balch S, Sterlin L, Thomas B, Camp S, Dunphy M, et al.
Cell Genom . 2022 Sep; 2(9). PMID: 36177448
Molecular profiling studies have enabled discoveries for metastatic prostate cancer (MPC) but have predominantly occurred in academic medical institutions and involved non-representative patient populations. We established the Metastatic Prostate Cancer...
9.
Schiantarelli J, Pappa T, Conway J, Crowdis J, Reardon B, Dietlein F, et al.
JCO Precis Oncol . 2022 Sep; 6:e2200183. PMID: 36075011
No abstract available.
10.
Kuiken H, Dhakal S, Selfors L, Friend C, Zhang T, Callari M, et al.
Oncogene . 2021 Oct; 41(1):112-124. PMID: 34703030
Intratumoral heterogeneity has been described for various tumor types and models of human cancer, and can have profound effects on tumor progression and drug resistance. This study describes an in-depth...