Jessica N Lancaster
Overview
Explore the profile of Jessica N Lancaster including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
171
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0
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Recent Articles
11.
Ki S, Thyagarajan H, Hu Z, Lancaster J, Ehrlich L
Eur J Immunol
. 2017 Jul;
47(11):1906-1917.
PMID: 28741728
Maturing thymocytes enter the thymic medulla, where they encounter numerous self-antigens presented by antigen presenting cells (APCs). Those thymocytes that are strongly self-reactive undergo either negative selection or diversion into...
12.
Lancaster J, Ehrlich L
Methods Mol Biol
. 2017 Mar;
1591:9-25.
PMID: 28349472
Thymocytes migrate through discrete compartments within the thymus, engaging in cellular interactions essential for their differentiation into functional and self-tolerant T cells. Thus, understanding the temporal and spatial behavior of...
13.
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation
Triplett T, Cardenas K, Lancaster J, Hu Z, Selden H, Jasso G, et al.
Proc Natl Acad Sci U S A
. 2016 Feb;
113(8):E1016-25.
PMID: 26862168
Primary T-cell acute lymphoblastic leukemia (T-ALL) cells require stromal-derived signals to survive. Although many studies have identified cell-intrinsic alterations in signaling pathways that promote T-ALL growth, the identity of endogenous...
14.
Hu Z, Lancaster J, Sasiponganan C, Ehrlich L
J Exp Med
. 2015 Sep;
212(11):1947-65.
PMID: 26417005
Autoimmunity results from a breakdown in central or peripheral tolerance. To establish central tolerance, developing T cells must enter the thymic medulla, where they scan antigen-presenting cells (APCs) displaying a...