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Jessica N Haines

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Recent Articles
1.
Chen S, Puri A, Bell B, Fritsche J, Palacios H, Balch M, et al.
Nat Commun . 2024 Mar; 15(1):2436. PMID: 38499535
Parkinson's disease (PD) is closely linked to α-synuclein (α-syn) misfolding and accumulation in Lewy bodies. The PDZ serine protease HTRA1 degrades fibrillar tau, which is associated with Alzheimer's disease, and...
2.
Kanan M, Sheehan P, Haines J, Gomez P, Dhuler A, Nadarajah C, et al.
JCI Insight . 2023 Nov; 9(2). PMID: 38032732
Circadian rhythm dysfunction is a hallmark of Parkinson disease (PD), and diminished expression of the core clock gene Bmal1 has been described in patients with PD. BMAL1 is required for...
3.
Davis A, Inman C, Wargel Z, Dube U, Freeberg B, Galluppi A, et al.
Sci Transl Med . 2020 Feb; 12(529). PMID: 32024799
Apolipoprotein E () ε4 genotype is associated with increased risk of dementia in Parkinson's disease (PD), but the mechanism is not clear, because patients often have a mixture of α-synuclein...