Jeremy J Ryan
Overview
Explore the profile of Jeremy J Ryan including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
35
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0
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Recent Articles
1.
Chen S, Puri A, Bell B, Fritsche J, Palacios H, Balch M, et al.
Nat Commun
. 2024 Mar;
15(1):2436.
PMID: 38499535
Parkinson's disease (PD) is closely linked to α-synuclein (α-syn) misfolding and accumulation in Lewy bodies. The PDZ serine protease HTRA1 degrades fibrillar tau, which is associated with Alzheimer's disease, and...
2.
Shrimali P, Chen S, Das A, Dreher R, Howard M, Ryan J, et al.
Acta Biomater
. 2023 Aug;
169:464-476.
PMID: 37586449
De novo designed peptides that self-assemble into cross-β rich fibrillar biomaterials have been pursued as an innovative platform for the development of adjuvant- and inflammation-free vaccines. However, they share structural...
3.
Howard M, Miller K, Sohn B, Ryan J, Xu A, Jackrel M
mBio
. 2023 May;
14(4):e0058723.
PMID: 37195208
Phenol-soluble modulins (PSMs) are the primary proteinaceous component of biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can lead to...
4.
Ryan J, Bao A, Bell B, Ling C, Jackrel M
Protein Sci
. 2021 May;
30(8):1667-1685.
PMID: 34010483
Hsp104, a yeast protein disaggregase, can be potentiated via numerous missense mutations at disparate locations throughout the coiled-coil middle domain (MD). Potentiated Hsp104 variants can counter the toxicity and misfolding...
5.
Ryan J, Sprunger M, Holthaus K, Shorter J, Jackrel M
J Biol Chem
. 2019 Nov;
294(46):17707.
PMID: 31732685
No abstract available.
6.
Ryan J, Sprunger M, Holthaus K, Shorter J, Jackrel M
J Biol Chem
. 2019 Jun;
294(29):11286-11296.
PMID: 31171724
FUS and EWSR1 are RNA-binding proteins with prion-like domains (PrLDs) that aggregate in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The and genes are also prone to chromosomal translocation...