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Jessica D S Grassmann

Explore the profile of Jessica D S Grassmann including associated specialties, affiliations and a list of published articles. Areas
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Citations 251
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Recent Articles
1.
Skelly D, Graham J, Cheng M, Furuta M, Walter A, Stoklasek T, et al.
bioRxiv . 2024 Jul; PMID: 39071392
Identifying host genetic factors modulating immune checkpoint inhibitor (ICI) efficacy has been experimentally challenging because of variations in both host and tumor genomes, differences in the microbiome, and patient life...
2.
Lawlor N, Nehar-Belaid D, Grassmann J, Stoeckius M, Smibert P, Stitzel M, et al.
Front Immunol . 2021 Apr; 12:636720. PMID: 33815388
Immune cell activation assays have been widely used for immune monitoring and for understanding disease mechanisms. However, these assays are typically limited in scope. A holistic study of circulating immune...
3.
Chen J, Grassmann J, Gowthaman U, Olyha S, Simoneau T, Berin M, et al.
J Allergy Clin Immunol . 2020 Jul; 147(2):470-483. PMID: 32709424
Anaphylaxis is a life-threatening allergic reaction caused by cross-linking of high-affinity IgE antibodies on the surface of mast cells and basophils. Understanding the cellular mechanisms that lead to high-affinity IgE...
4.
Gowthaman U, Chen J, Zhang B, Flynn W, Lu Y, Song W, et al.
Science . 2019 Aug; 365(6456). PMID: 31371561
Cross-linking of high-affinity immunoglobulin E (IgE) results in the life-threatening allergic reaction anaphylaxis. Yet the cellular mechanisms that induce B cells to produce IgE in response to allergens remain poorly...