Jessica C Graham
Overview
Explore the profile of Jessica C Graham including associated specialties, affiliations and a list of published articles.
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12
Citations
63
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Recent Articles
1.
Graham J, Bercu J, Fortin M, Kiorpes A, Sethi S, Roy R
Int J Toxicol
. 2025 Feb;
:10915818251319250.
PMID: 39951653
Have you ever reflected on your career or other experiences and thought, if I knew 10 or 20 years ago, what I know now, it would have enabled me to...
2.
Graham J, Anand S, Bercu J, Besenhofer L, de Zafra C, Feng Y, et al.
Regul Toxicol Pharmacol
. 2024 Sep;
153:105700.
PMID: 39243930
Protein A (PA) is a bacterial cell wall component of Staphylococcus aureus whose function is to bind to Immunoglobulin G (IgG). Given its ability to bind IgG as well as...
3.
Kostal J, Voutchkova-Kostal A, Bercu J, Graham J, Hillegass J, Masuda-Herrera M, et al.
Chem Res Toxicol
. 2024 Jul;
37(8):1404-1414.
PMID: 39069667
Skin sensitization is a critical end point in occupational toxicology that necessitates the use of fast, accurate, and affordable models to aid in establishing handling guidance for worker protection. While...
4.
Graham J, Wong L, Adedeji A, Kusi A, Lee B, Lee D, et al.
Animals (Basel)
. 2023 Dec;
13(24).
PMID: 38136900
Based on the current state of science, the use of animals remains essential in bringing safe and effective medicines to patients. Respect for laboratory animal welfare and the application of...
5.
Graham J, Trejo-Martin A
J Org Chem
. 2022 Nov;
87(22):14993-14994.
PMID: 36398527
No abstract available.
6.
Graham J, Trejo-Martin A, Chilton M, Kostal J, Bercu J, Beutner G, et al.
Chem Res Toxicol
. 2022 May;
35(6):1011-1022.
PMID: 35532537
Peptide couplers (also known as amide bond-forming reagents or coupling reagents) are broadly used in organic chemical syntheses, especially in the pharmaceutical industry. Yet, occupational health hazards associated with this...
7.
Graham J, Powley M, Udovic E, Glowienke S, Nicolette J, Parris P, et al.
Regul Toxicol Pharmacol
. 2021 Aug;
126:105023.
PMID: 34363920
The presence of impurities in drugs is unavoidable. As impurities offer no direct benefit to the patient, it is critical that impurities do not compromise patient safety. Current guidelines on...
8.
Graham J, Rodas M, Hillegass J, Schulze G
Regul Toxicol Pharmacol
. 2020 Nov;
119:104816.
PMID: 33166621
Acute oral toxicity (AOT) information is utilized to categorize compounds according to the severity of their hazard and used to inform risk assessments for human health and the environment. Given...
9.
Graham J, Hillegass J, Schulze G
Regul Toxicol Pharmacol
. 2020 Nov;
118:104813.
PMID: 33144077
In order to develop new and effective medicines, pharmaceutical companies must be modality agnostic. As science reveals an enhanced understanding of biological processes, new therapeutic modalities are becoming important in...
10.
Kuhtreiber W, Takahashi H, Keefe R, Song Y, Tran L, Luck T, et al.
iScience
. 2020 May;
23(5):101085.
PMID: 32380424
Myc has emerged as a pivotal transcription factor for four metabolic pathways: aerobic glycolysis, glutaminolysis, polyamine synthesis, and HIF-1α/mTOR. Each of these pathways accelerates the utilization of sugar. The BCG...